Seibel Eric J, Smithwick Quinn Y J
Department of Mechanical Engineering, Human Interface Technology Laboratory, University of Washington, Seattle, Washington.
Lasers Surg Med. 2002;30(3):177-83. doi: 10.1002/lsm.10029.
To advance the field of minimally invasive medical procedures, an ideal endoscope should provide high-resolution images with variable magnification from an ultra-thin package, while adding depth cues and integrating optical diagnoses and therapies. Satisfying all these requirements is extremely difficult using commercial endoscopes. A new imaging technology is introduced that uses directed laser illumination, which is scanned at the distal end of a flexible endoscope.
STUDY DESIGN/MATERIALS AND METHODS: A single-mode optical fiber is driven in vibratory resonance using a piezoelectric actuator. The emitted laser light is scanned in two-dimensions over test specimens. Digital images are constructed by detecting optical power one pixel at a time.
Unique features of the fiber scanning scope are rapidly changing magnification, enhanced topographic detail, and concurrent fluorescence imaging, which are demonstrated and discussed.
This fiber scanning scope has the potential for pixel-accurate delivery of high quality laser radiation, allowing the future integration of imaging with diagnosis and therapy.
为推动微创医疗程序领域的发展，理想的内窥镜应能从超薄封装中提供具有可变放大率的高分辨率图像，同时增加深度线索并整合光学诊断与治疗功能。使用商用内窥镜很难满足所有这些要求。本文介绍了一种新的成像技术，该技术使用定向激光照明，并在柔性内窥镜的远端进行扫描。
研究设计/材料与方法：使用压电致动器驱动单模光纤产生振动共振。发射的激光在测试样本上进行二维扫描。通过一次检测一个像素的光功率来构建数字图像。
光纤扫描内窥镜的独特特性包括快速变化的放大率、增强的地形细节和同步荧光成像，本文对此进行了展示和讨论。
这种光纤扫描内窥镜具有以像素精度输送高质量激光辐射的潜力，有望在未来实现成像与诊断及治疗的整合。
