变应性和非变应性鼻炎的炎症模式。

Inflammatory patterns of allergic and nonallergic rhinitis.

作者信息

Sobol S E, Christodoulopoulos P, Hamid Q A

机构信息

Meakins-Christie Laboratories, McGill University, 3626 St. Urbain Street, Montreal, Quebec, H2X 2P2, Canada.

出版信息

Curr Allergy Asthma Rep. 2001 May;1(3):193-201. doi: 10.1007/s11882-001-0005-7.

DOI:10.1007/s11882-001-0005-7

PMID:11892036

Abstract

Rhinitis is a chronic condition of the nasal mucosa that affects a large segment of the population. The symptoms of rhinitis occur in a variety of sinonasal conditions, which may be broadly classified as allergic (seasonal or perennial) or nonallergic (infectious or a number of noninfectious etiologies) based on the presence or absence of atopy. The cytokine profile and inflammatory patterns underlying these two conditions vary because of certain differences in their pathophysiology as discussed in this review.

摘要

鼻炎是一种影响很大一部分人群的鼻黏膜慢性疾病。鼻炎症状出现在多种鼻窦疾病中，根据是否存在特应性，这些疾病大致可分为过敏性（季节性或常年性）或非过敏性（感染性或多种非感染性病因）。如本综述所述，由于这两种情况在病理生理学上存在某些差异，其细胞因子谱和炎症模式也有所不同。