斑贴试验在特应性皮炎中对化学和蛋白质变应原的作用。

The role of patch testing for chemical and protein allergens in atopic dermatitis.

作者信息

Nedorost S T, Cooper K D

机构信息

Department of Dermatology, University Hospitals of Cleveland, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA.

出版信息

Curr Allergy Asthma Rep. 2001 Jul;1(4):323-8. doi: 10.1007/s11882-001-0043-1.

DOI:10.1007/s11882-001-0043-1

PMID:11892054

Abstract

Many patients who present for evaluation of allergic contact dermatitis have an atopic diathesis. Although the immunologic basis of atopic dermatitis differs from that of allergic contact dermatitis--and patients with atopic dermatitis are less easily sensitized under experimental conditions--atopic patients do develop allergic contact dermatitis, and patch testing is a valuable part of their medical care. Delayed (7-day) patch test readings are especially important in atopic patients to distinguish allergy from irritancy and to evaluate for steroid allergy. The utility of atopy patch tests to aeroallergens such as dust mite is increasingly recognized; aeroallergens may be the cause of a type of protein contact dermatitis.

摘要

许多前来评估过敏性接触性皮炎的患者都有特应性素质。虽然特应性皮炎的免疫基础与过敏性接触性皮炎不同，而且在实验条件下特应性皮炎患者较难致敏，但特应性患者确实会发生过敏性接触性皮炎，斑贴试验是其医疗护理的重要组成部分。对于特应性患者，延迟（7天）的斑贴试验读数对于区分过敏与刺激以及评估类固醇过敏尤为重要。对尘螨等气源性变应原进行特应性斑贴试验的效用日益得到认可；气源性变应原可能是一种蛋白质接触性皮炎的病因。