Rodrigues Rosana Neves Dos Santos, Melo João Ferreira, Montealegre Federico, Hahnstadt Ruppert Ludwig, Pires Mario Cezar
Serviço de Alergia e Imunologia, Hospital do Servidor Público Estadual, São Paulo, SP, Brasil.
An Bras Dermatol. 2011 Jan-Feb;86(1):37-43. doi: 10.1590/s0365-05962011000100004.
Atopic dermatitis is an inflammatory skin disease that can be triggered by many factors. Several reports confirm the role of airborne allergic agents as aggravating or triggering factors. The patch test with airborne allergic agents or the atopy patch test was suggested to evaluate the role of these allergens in atopic dermatitis.
This study aimed at evaluating the positivity of the atopy patch test in patients with atopic dermatitis.
We evaluated 50 patients with atopic dermatitis and 45 with allergic rhinitis, the atopy patch test was performed in these patients with extracts of Dermatophagoides pteronissynus, Dermatophagoides farinae and Blomia tropicalis, as well as immediate skin prick tests for the same allergens with cat and dog epithelia and fungi.
It was found that the atopy patch test with dust mites showed higher positivity in individuals with atopic dermatitis when compared to those with allergic rhinitis.
The atopy patch test shows statistically significant results when performed with dust mites in patients with atopic dermatitis, p = 0.035, odds ratio (OR) = 3.35 and CI (95%) = [1.18, 9, 47].
特应性皮炎是一种可由多种因素引发的炎症性皮肤病。多项报告证实空气传播的变应原作为加重或触发因素的作用。有人建议采用空气传播变应原斑贴试验或特应性斑贴试验来评估这些变应原在特应性皮炎中的作用。
本研究旨在评估特应性皮炎患者特应性斑贴试验的阳性率。
我们评估了50例特应性皮炎患者和45例变应性鼻炎患者,对这些患者进行了用粉尘螨、屋尘螨和热带无爪螨提取物的特应性斑贴试验,以及对相同变应原与猫和狗上皮及真菌进行的即时皮肤点刺试验。
发现与变应性鼻炎患者相比,特应性皮炎患者进行的粉尘螨特应性斑贴试验显示出更高的阳性率。
特应性皮炎患者用粉尘螨进行特应性斑贴试验时显示出具有统计学意义的结果,p = 0.035,比值比(OR)= 3.35,95%置信区间(CI)= [1.18, 9.47]。