用人多形核白细胞弹性蛋白酶消化人IgG类风湿因子体外产生具有生物活性的Fab2样片段。 - Suppr | 超能文献

In vitro production of a biologically active Fab2-like fragment by digestion of human IgG rheumatoid factor with human polymorphonuclear leukocyte elastase.

作者信息

Prince H E, Folds J D, Spitznagel J K

出版信息

Mol Immunol. 1979 Nov;16(11):975-8. doi: 10.1016/0161-5890(79)90099-3.

DOI:10.1016/0161-5890(79)90099-3

Abstract

摘要

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In vitro production of a biologically active Fab2-like fragment by digestion of human IgG rheumatoid factor with human polymorphonuclear leukocyte elastase.用人多形核白细胞弹性蛋白酶消化人IgG类风湿因子体外产生具有生物活性的Fab2样片段。

Mol Immunol. 1979 Nov;16(11):975-8. doi: 10.1016/0161-5890(79)90099-3.

2

A comparative analysis of human IgM rheumatoid factor degradation by purified elastase and total granule extracts from human polymorphonuclear leukocytes.纯化弹性蛋白酶与人多形核白细胞总颗粒提取物对人 IgM 类风湿因子降解作用的比较分析。

Inflammation. 1980 Mar;4(1):27-35. doi: 10.1007/BF00914100.

3

Interaction of human polymorphonuclear leukocyte elastase with human IgM In vitro production of an Fabmu-like fragment.人多形核白细胞弹性蛋白酶与人IgM的相互作用：Fabμ样片段的体外产生

Mol Immunol. 1979 May;16(5):301-6. doi: 10.1016/0161-5890(79)90130-5.

4

Cathepsin G from human polymorphonuclear leukocytes cleaves human IgM.

Mol Immunol. 1982 May;19(5):719-27. doi: 10.1016/0161-5890(82)90373-x.

5

Limited cleavage of human immunoglobulins by elastase of human neutrophil polymorphonuclear granulocytes. Possible modulator of immune complex disease.人中性粒细胞多形核粒细胞弹性蛋白酶对人免疫球蛋白的有限切割。免疫复合物疾病的可能调节因子。

Lab Invest. 1978 Oct;39(4):313-21.

6

Cleavage of IgG by elastase-like protease (ELP) of human polymorphonuclear leukocytes (PMN): isolation and characterization of Fab and Fc fragments and low-molecular-weight peptides. Stimulation of granulocyte function by ELP-derived Fab and Fc fragments.人多形核白细胞（PMN）的类弹性蛋白酶（ELP）对IgG的裂解：Fab和Fc片段及低分子量肽的分离与鉴定。ELP衍生的Fab和Fc片段对粒细胞功能的刺激作用。

Immunobiology. 1982 May;161(5):507-23. doi: 10.1016/S0171-2985(82)80053-3.

7

Interaction of human polymorphonuclear leukocyte (PMN) elastase with human IgM. Production of a factor enhancing PMN migration in vitro.人多形核白细胞（PMN）弹性蛋白酶与人类IgM的相互作用。体外产生一种增强PMN迁移的因子。

Immunol Commun. 1980;9(1):23-32. doi: 10.3109/08820138009050804.

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Proteolysis of human IgG by human polymorphonuclear leucocyte elastase produces an Fc fragment with in vitro biological activity.人多形核白细胞弹性蛋白酶对人免疫球蛋白G的蛋白水解作用产生具有体外生物活性的Fc片段。

Clin Exp Immunol. 1979 Jul;37(1):162-8.

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Regulation of neutrophil functions by elastase-generated IgG fragments.弹性蛋白酶产生的IgG片段对中性粒细胞功能的调节

Arch Immunol Ther Exp (Warsz). 1992;40(1):43-7.

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The Fc binding site for streptococcal protein G is in the C gamma 2-C gamma 3 interface region of IgG and is related to the sites that bind staphylococcal protein A and human rheumatoid factors.链球菌蛋白G的Fc结合位点位于IgG的Cγ2-Cγ3界面区域，且与结合葡萄球菌蛋白A和人类类风湿因子的位点相关。

J Immunol. 1989 Jul 15;143(2):565-70.

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Pulm Med. 2011;2011:826160. doi: 10.1155/2011/826160. Epub 2011 Mar 31.

2

A comparative analysis of human IgM rheumatoid factor degradation by purified elastase and total granule extracts from human polymorphonuclear leukocytes.纯化弹性蛋白酶与人多形核白细胞总颗粒提取物对人 IgM 类风湿因子降解作用的比较分析。

Inflammation. 1980 Mar;4(1):27-35. doi: 10.1007/BF00914100.

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The biological properties of immunoglobulin G and its split products [F(ab')2 and Fab].免疫球蛋白G及其裂解产物[F(ab')2和Fab]的生物学特性。

Klin Wochenschr. 1983 Aug 1;61(15):723-36. doi: 10.1007/BF01497399.