DNA复制与染色质

DNA replication and chromatin.

作者信息

Gerbi Susan A, Bielinsky Anja Katrin

机构信息

Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Division of Biology and Medicine, Providence, Rhode Island 02912, USA.

出版信息

Curr Opin Genet Dev. 2002 Apr;12(2):243-8. doi: 10.1016/s0959-437x(02)00292-7.

DOI:10.1016/s0959-437x(02)00292-7

PMID:11893499

Abstract

The study of DNA replication in eukaryotic chromosomes has revealed a multitude of different regulatory levels. Nuclear and chromosomal location as well as chromatin structure may affect the activity of replication origins and their modulation during development.

摘要

对真核生物染色体中DNA复制的研究揭示了众多不同的调控水平。核及染色体定位以及染色质结构可能会影响复制起点的活性及其在发育过程中的调控。