Vinokur M L, Gosh T E
Vopr Onkol. 1975;21(10):39-45.
An analysis of clinical and colposcopic findings in 107 patients with early forms of invasive cancer of the uterine cervix with deep invasion not more than 3 mm (st. 1-a) and their correlation with the results of histological assay enabled the authors to give the clinico-morphological characteristics of this stage of the lesion. It was found that 40% of patients had complaints pathognomonic for a malignant process; 91.6% of patients showed visually recognizable but nonspecific changes in the cervix; in 94% of cases colposcopy revealed cancer suspicious changes of the common and increased atypical epithelium type. In 53.3% cancer foci are so limited that these would be removed by primary biopsy. Metastases in regional lymph nodes were detected in 1.6%. Limited foci of the cancer and extremly rare metastases spread in regional lymph nodes justify the use of hysterectomy solely in treatment of such patients.
对107例宫颈早期浸润癌且浸润深度不超过3mm（1-a期）患者的临床和阴道镜检查结果进行分析，并将其与组织学检测结果相关联，使作者能够给出该病变阶段的临床形态学特征。结果发现，40%的患者有恶性病变的特征性主诉；91.6%的患者宫颈有肉眼可见但非特异性的变化；94%的病例阴道镜检查显示常见且非典型上皮类型增加的可疑癌症变化。53.3%的癌灶局限，可通过初次活检切除。1.6%的患者检测到区域淋巴结转移。癌灶局限且区域淋巴结转移极少，证明仅行子宫切除术治疗此类患者是合理的。
