McLucas B, Reed R A, Goodwin S, Rappaport A, Adler L, Perrella R, Dalrymple J
Department of Obstetrics and Gynecology, University of California at Los Angeles, School of Medicine, Los Angeles, CA 90095, USA.
Br J Radiol. 2002 Feb;75(890):122-6. doi: 10.1259/bjr.75.890.750122.
Uterine artery embolisation has been described as successful only when both arteries are embolised. However, results in patients with one congenitally absent or previously ligated artery are unknown. Women suffering from symptomatic uterine myomata were treated at a university teaching hospital, a community hospital and an outpatient surgery centre. Retrospective review of patient response to embolisation was assessed by chart review and questionnaire. Uterine and dominant fibroid size response was assessed by comparing pre- and post-embolisation ultrasound examinations. This study analysed three patient groups within the general population: those who underwent unilateral embolisation because of technical failure, those who ultimately underwent bilateral embolisation after initial technical failure and those who underwent unilateral embolisation because of an absent uterine artery. 12 patients underwent unilateral embolisation, 4 of whom underwent this procedure because of an absent uterine artery. Three of these four patients had a congenitally absent uterine artery arising from the internal iliac artery and all three experienced successful outcomes. The fourth patient had a previously ligated internal iliac artery and her symptoms worsened after the procedure. Eight patients had unilateral embolisation due to technical failure. Five of these patients underwent a subsequent procedure during which the contralateral uterine artery was embolised. Four of these five patients had successful outcomes and one was lost to follow-up. Another of the eight patients suffered an arterial injury leading to technical failure, and was lost to follow-up. Of the two remaining patients with unilateral technical failure, only one had a successful outcome. This study concluded that patients who undergo unilateral embolisation for technical reasons should be offered a second embolisation procedure shortly after the initial procedure. Patients with a congenitally absent uterine artery may respond with similar success to those who underwent bilateral embolisation. In contrast, the patient with a previously ligated internal iliac artery failed. The numbers in this study are too small for statistical analysis and subsequent studies should be performed to confirm these findings.
子宫动脉栓塞术只有在双侧动脉均被栓塞时才被认为是成功的。然而,对于一侧先天性缺如或先前已结扎动脉的患者,其治疗结果尚不清楚。在一家大学教学医院、一家社区医院和一个门诊手术中心对有症状的子宫肌瘤女性进行了治疗。通过病历审查和问卷调查对患者对栓塞术的反应进行回顾性评估。通过比较栓塞术前和术后的超声检查来评估子宫及主要肌瘤大小的变化。本研究分析了普通人群中的三组患者:因技术失败而接受单侧栓塞的患者、最初技术失败后最终接受双侧栓塞的患者以及因子宫动脉缺如而接受单侧栓塞的患者。12例患者接受了单侧栓塞,其中4例因子宫动脉缺如而接受该手术。这4例患者中有3例子宫动脉先天性缺如,起源于髂内动脉,且这3例患者均获得了成功的治疗结果。第4例患者的髂内动脉先前已被结扎,术后症状加重。8例患者因技术失败接受了单侧栓塞。其中5例患者随后接受了对侧子宫动脉栓塞手术。这5例患者中有4例获得了成功的治疗结果,1例失访。8例患者中的另1例发生动脉损伤导致技术失败,失访。其余2例单侧技术失败的患者中,只有1例获得了成功的治疗结果。本研究得出结论,因技术原因接受单侧栓塞的患者应在初次手术后不久接受第二次栓塞手术。子宫动脉先天性缺如的患者可能会取得与接受双侧栓塞的患者类似的成功治疗结果。相比之下,髂内动脉先前已被结扎动脉的患者治疗失败。本研究中的病例数过少,无法进行统计分析,后续应开展研究以证实这些发现。