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子宫肌瘤栓塞术的术中并发症及其对长期临床结局的影响。

Intraprocedural complications of uterine fibroid embolisation and their impact on long-term clinical outcome.

作者信息

Javorka V, Malik M, Mizickova M, Palenik S, Mikula P, Redecha M

出版信息

Bratisl Lek Listy. 2019;120(10):734-738. doi: 10.4149/BLL_2019_122.

Abstract

OBJECTIVES

Authors evaluate the impact of intraprocedural complications on successful technical realisation and long-term clinical outcome of the uterine fibroid embolisation.

BACKGROUND

The uterine artery embolisation (UAE) has become an accepted treatment method for uterine fibroids. In general, the unilateral embolisation is considered to be insufficient due to poor clinical effect.

METHODS

Overall, 165 uterine artery embolisations were analysed (retrospectively-prospectively) in 163 female patients. Intraprocedural complications and their impact on the possibility to perform bilateral embolisationwere evaluated. In patients with unscheduled unilateral embolisation, short-term as well as long-term clinical effects were observed with mean follow-up period of 41 months.

RESULTS

The bilateral uterine artery embolisation was possible in 95.7 % (95 %, CI 91.3-99.4 %) procedures. The unilateral embolisation was reported in 7 procedures (4.3 %, CI 1.2-8.3 %) and reasons were following: resistant arterial spasm in 4 patients (2.5 %, CI 0.7 %-5.3 %) and impossible catheterisation due to unfavourable anatomic situation in 3 patients (1.8 %, CI 0.3-4.1 %). Other complications, such as dissection and perforation, did not affect the successful technical realisation. The long-term clinical effect of unscheduled unilateral embolisation was reported in 5 patients.

CONCLUSION

The results of our series of unscheduled unilateral uterine fibroid embolisation had high long-term clinical success rate. In way of unscheduled unilateral embolisation, we recommend MRI follow-up and reintervention only in way of persistence or recurrence of symptoms with concurrent MRI finding of residual fibroids(Tab. 5, Fig. 3, Ref. 12).

摘要

目的

作者评估术中并发症对子宫肌瘤栓塞术技术成功实现及长期临床结局的影响。

背景

子宫动脉栓塞术(UAE)已成为一种被认可的子宫肌瘤治疗方法。一般来说,由于临床效果不佳,单侧栓塞被认为是不够的。

方法

对163例女性患者的165次子宫动脉栓塞术进行了(回顾性-前瞻性)分析。评估术中并发症及其对进行双侧栓塞可能性的影响。对于计划外单侧栓塞的患者,观察短期和长期临床效果,平均随访期为41个月。

结果

95.7%(95%,CI 91.3 - 99.4%)的手术可行双侧子宫动脉栓塞。7例手术(4.3%,CI 1.2 - 8.3%)报告为单侧栓塞,原因如下:4例患者(2.5%,CI 0.7% - 5.3%)出现顽固性动脉痉挛,3例患者(1.8%,CI 0.3 - 4.1%)因解剖情况不利导致无法插管。其他并发症,如夹层和穿孔,不影响技术成功实现。5例患者报告了计划外单侧栓塞的长期临床效果。

结论

我们这一系列计划外单侧子宫肌瘤栓塞术的结果具有较高的长期临床成功率。对于计划外单侧栓塞,我们建议仅在症状持续或复发且MRI发现残留肌瘤的情况下进行MRI随访和再次干预(表5,图3,参考文献12)。

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