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[快电子对腹水瘤NK/Ly细胞及荷瘤小鼠脾脏细胞核酸水平和RNA生物合成的影响]

[Influence of fast electrons on the nucleic acid level and the biosynthsis of RNA in cells of the ascites tumor NK/Ly and the spleen of tumor-bearing mice].

作者信息

Zerov Iu P, Zelenkova N K, Akimov A A, Seĭts I F

出版信息

Vopr Onkol. 1975;21(9):72-6.

PMID:1189366
Abstract

The results of investigations on total nucleic acids content and RNA turnover in the cells of tumor NK/Ly and of the spleen in tumor-bearing mice after single exposure to fast electrons are described. In every case the irradiation results in reliable changes of parameters under study. The pattern of changes in nucleic acids content and turnover in the spleen after the exposure to fast electrons is in a good agreement with the available data concerning the influence of x- and y-radiation. The irradiation action on nucleic acids content and turnover in ascites tumor NK/Ly cells is qualitatively and quantitatively similar to that in splenic cells.

摘要

描述了单次暴露于快电子后荷瘤小鼠肿瘤NK/Ly细胞和脾脏细胞中总核酸含量及RNA周转的研究结果。在每种情况下,辐照都会导致所研究参数发生可靠的变化。暴露于快电子后脾脏中核酸含量和周转的变化模式与有关x射线和y射线影响的现有数据高度一致。辐照对腹水肿瘤NK/Ly细胞中核酸含量和周转的作用在质量和数量上与脾细胞中的相似。

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