Gutoranov G
Vutr Boles. 1975;14(1):40-4.
The values of 17-ketosteroids (according toe Drekter, Pearson, Bartezak, modification of Kukuskina and Gurjeva), 5-hydroxyindole acetic acid (according to Sjoerdsma, Weisbach and Udenfriend) and 3-methoxy, 4-hydroxyvanillyl mandelic acid (according to Pisano et al, modification of Georges) were followed up in the 24-hour urine of 37 female-weavers (subdivided into two groups--healthy and neurotics) and 15 males--operators of control boards from the Chemical Combinate--Vratza. The urine was tested also according to the method of Wisser and Stamm, 1970, in mgr/2 hours. The comparison of the metabolite values before and after work revealed an increase of 17-ketosteroids and vanillyl-mandelic acid after neuro-sensory loading, especially in neurotics. Lower values, at the end of the working shift, were found for the 5-hydroyindole acetic acid, with the exception of those of the neurotics, that were elevated--an increased utilization of serotonin is relied on.
对37名女织布工（分为健康组和神经症组）以及15名来自弗拉察化学联合企业控制板操作员的男性，随访了其24小时尿液中17 - 酮类固醇（根据德雷克特、皮尔逊、巴尔特扎克对库库斯基纳和古尔耶娃方法的改进）、5 - 羟吲哚乙酸（根据斯约德斯马、魏斯巴赫和乌登弗里德方法）以及3 - 甲氧基 - 4 - 羟基香草扁桃酸（根据皮萨诺等人对乔治方法的改进）的值。尿液还按照维泽尔和施塔姆1970年的方法进行检测，单位为毫克/2小时。工作前后代谢物值的比较显示，神经感觉负荷后17 - 酮类固醇和香草扁桃酸增加，尤其是在神经症患者中。除神经症患者的值升高外，工作班次结束时5 - 羟吲哚乙酸的值较低，这依赖于血清素利用率的增加。
