[Excretion of some metabolites of catecholamine, serotonin and steroid hormones following neurosensory loading].

The values of 17-ketosteroids (according toe Drekter, Pearson, Bartezak, modification of Kukuskina and Gurjeva), 5-hydroxyindole acetic acid (according to Sjoerdsma, Weisbach and Udenfriend) and 3-methoxy, 4-hydroxyvanillyl mandelic acid (according to Pisano et al, modification of Georges) were followed up in the 24-hour urine of 37 female-weavers (subdivided into two groups--healthy and neurotics) and 15 males--operators of control boards from the Chemical Combinate--Vratza. The urine was tested also according to the method of Wisser and Stamm, 1970, in mgr/2 hours. The comparison of the metabolite values before and after work revealed an increase of 17-ketosteroids and vanillyl-mandelic acid after neuro-sensory loading, especially in neurotics. Lower values, at the end of the working shift, were found for the 5-hydroyindole acetic acid, with the exception of those of the neurotics, that were elevated--an increased utilization of serotonin is relied on.