Kaiser Robyn M, Garman Robert L, Bruce Michael G, Weyant Robbin S, Ashford David A
National Center for Infectious Disease, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Emerg Infect Dis. 2002 Feb;8(2):171-4. doi: 10.3201/eid0802.010139.
From 1974 to 1998, 22 isolates of an unusual bacterium, designated as CDC nonoxidizer 1 group (NO-1), were sent to the Centers for Disease Control and Prevention for identification. The organism's phenotypic characteristics were similar to asaccharolytic strains of Acinetobacter, but differed in their cellular morphology and cellular fatty acid profile. We report here on NO-1's clinical and epidemiologic significance. In all cases, isolates were recovered from an animal bite wound; 17 (77%) were isolated from a dog bite wound, 4 (18%) from a cat bite wound, and one (5%) from an unspecified animal bite. Clinical data were retrieved and reviewed for 12 (55%) of the 22 bite victims. None of the patients had pre-existing conditions associated with immunosuppression. Seven (58%) patients were hospitalized for a median stay of 4 days (range, 2 to 11 days). The median time between bite to the worsening of symptoms was 17.5 hours (range, 3 to 78 hours). All patients recovered following antibiotic treatment.
1974年至1998年期间，22株异常细菌被送至疾病控制与预防中心进行鉴定，该细菌被指定为疾病控制中心非氧化菌1组（NO-1）。该微生物的表型特征与不动杆菌的非糖酵解菌株相似，但其细胞形态和细胞脂肪酸谱有所不同。我们在此报告NO-1的临床和流行病学意义。在所有病例中，分离株均从动物咬伤伤口中分离得到；17株（77%）从狗咬伤伤口中分离得到，4株（18%）从猫咬伤伤口中分离得到，1株（5%）从未指明的动物咬伤中分离得到。对22名咬伤受害者中的12名（55%）的临床数据进行了检索和审查。所有患者均无与免疫抑制相关的既往病史。7名（58%）患者住院，中位住院时间为4天（范围为2至11天）。咬伤至症状恶化的中位时间为17.5小时（范围为3至78小时）。所有患者经抗生素治疗后均康复。
