Xiong Guoxiang, Hiramatsu Takahito, Nagao Soichi
Department of Physiology, Jichi Medical School, 3311-1 Yakushiji, Minamikawachi-machi, Tochigi 329-0498, Japan.
Neurosci Lett. 2002 Apr 12;322(3):173-6. doi: 10.1016/s0304-3940(02)00108-8.
The relationship between axons derived from the prearcuate region and pontine neurons projecting to contralateral cerebellar hemispheric lobule VII, lobulus petrosus (LP) of the paraflocculus or the dorsal paraflocculus (DPFl) was investigated in the monkey. The frontopontine axons were labeled with biotinylated dextran and pontocerebellar neurons with cholera toxin subunit B or fast blue. Labeled frontopontine axons and terminals were seen in the dorsal, medial, paramedian and dorsolateral parts of the pontine nuclei. The distribution of the labeled frontopontine axons overlapped that of labeled neurons projecting to hemispheric lobule VII but did not overlap that of labeled neurons projecting to LP or DPFl. The pathway from the prearcuate region to hemispheric lobule VII may provide an anatomical substrate for the involvement of hemispheric lobule VII in voluntary eye movements.
在猴子中研究了源自弓状前区的轴突与投射到对侧小脑半球小叶VII、旁绒球的岩部小叶（LP）或背侧旁绒球（DPFl）的脑桥神经元之间的关系。额桥轴突用生物素化葡聚糖标记，脑桥小脑神经元用霍乱毒素B亚单位或快蓝标记。在脑桥核的背侧、内侧、旁正中及背外侧部分可见标记的额桥轴突和终末。标记的额桥轴突的分布与投射到半球小叶VII的标记神经元的分布重叠，但与投射到LP或DPFl的标记神经元的分布不重叠。从弓状前区到半球小叶VII的通路可能为半球小叶VII参与随意眼球运动提供解剖学基础。
