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冠状动脉瘘的管理。患者选择及经导管封堵结果。

Management of coronary artery fistulae. Patient selection and results of transcatheter closure.

作者信息

Armsby Laurie R, Keane John F, Sherwood Megan C, Forbess Joseph M, Perry Stanton B, Lock James E

机构信息

Department of Cardiology, The Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

出版信息

J Am Coll Cardiol. 2002 Mar 20;39(6):1026-32. doi: 10.1016/s0735-1097(02)01742-4.

Abstract

OBJECTIVES

We report short-term findings in 33 patients after transcatheter closure (TCC) of coronary artery fistulae (CAF) and compare our results with those reported in the recent transcatheter and surgical literature.

BACKGROUND

Transcatheter closure of CAF has been advocated as a minimally invasive alternative to surgery.

METHODS

We reviewed all patients presenting with significant CAF between January 1988 and August 2000. Those with additional complex cardiac disease requiring surgical management were excluded.

RESULTS

Of 39 patients considered for TCC, occlusion devices were placed in 33 patients (85%) at 35 procedures and included coils in 28, umbrella devices in 6 and a Grifka vascular occlusion device in 1. Post-deployment angiograms demonstrated complete occlusion in 19, trace in 11, or small residual flow in 5. Follow-up echocardiograms (median, 2.8 years) in 27 patients showed no flow in 22 or small residual flow in 5. Of the 6 patients without follow-up imaging, immediate post-deployment angiograms showed complete occlusion in 5 or small residual flow in 1. Thus, complete occlusion was accomplished in 27 patients (82%). Early complications included transient ST-T wave changes in 5, transient arrhythmias in 4 and single instances of distal coronary artery spasm, fistula dissection and unretrieved coil embolization. There were no deaths or long-term morbidity. Device placement was not attempted in 6 patients (15%), because of multiple fistula drainage sites in 4, extreme vessel tortuosity in 1 and an intracardiac hemangioma in 1.

CONCLUSIONS

A comparison of our results with those in the recent transcatheter and surgical literature shows similar early effectiveness, morbidity and mortality. From data available, TCC of CAF is an acceptable alternative to surgery in most patients.

摘要

目的

我们报告了33例冠状动脉瘘(CAF)经导管封堵术(TCC)后的短期结果,并将我们的结果与近期经导管和外科手术文献报道的结果进行比较。

背景

经导管封堵CAF已被提倡作为一种微创的手术替代方法。

方法

我们回顾了1988年1月至2000年8月间所有患有显著CAF的患者。排除那些伴有需要手术治疗的其他复杂心脏疾病的患者。

结果

在考虑进行TCC的39例患者中,33例患者(85%)接受了35次封堵手术,其中28例使用了弹簧圈,6例使用了伞形装置,1例使用了Grifka血管封堵装置。封堵术后血管造影显示19例完全封堵,11例微量分流,5例有少量残余血流。27例患者的随访超声心动图(中位数为2.8年)显示,22例无血流,5例有少量残余血流。在6例未进行随访成像的患者中,封堵术后即刻血管造影显示5例完全封堵,1例有少量残余血流。因此,27例患者(82%)实现了完全封堵。早期并发症包括5例短暂性ST-T波改变,4例短暂性心律失常,以及1例远端冠状动脉痉挛、瘘管夹层和未取出的弹簧圈栓塞。无死亡病例或长期发病情况。6例患者(15%)未尝试进行装置置入,原因是4例有多处分流部位,1例血管极度迂曲,1例有心内血管瘤。

结论

将我们的结果与近期经导管和外科手术文献报道的结果进行比较,显示出相似的早期有效性、发病率和死亡率。根据现有数据,CAF的TCC对大多数患者来说是一种可接受的手术替代方法。

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