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左前降支双先天性异常:一种闭合动脉瘤和瘘管宽颈的技术改良——病例报告

Double congenital abnormalities of left anterior descending artery: a technical modification for closing wide neck of aneurysm and fistulae-a case report.

作者信息

Çetin Güvenç Rengin, Al Arfaj Abdullah Ayar, Doğan Demet, Özer Nihat

机构信息

Department of Internal Medical Sciences, Division of Cardiology, Istanbul Okan University School of Medicine, Tepeören Mahallesi Tuzla Kampüsü, Tuzla/Istanbul 34959, Turkey.

Department of Internal Medical Sciences, Division of Radiology, Istanbul Okan University School of Medicine, Tepeören Mahallesi Tuzla Kampüsü, Tuzla/Istanbul 34959, Turkey.

出版信息

Eur Heart J Case Rep. 2025 May 26;9(6):ytaf263. doi: 10.1093/ehjcr/ytaf263. eCollection 2025 Jun.

DOI:10.1093/ehjcr/ytaf263
PMID:40599200
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12209800/
Abstract

BACKGROUND

The duplication of the left anterior descending coronary artery and coronary artery-to-pulmonary artery fistulae are infrequent congenital anomalies described in literature. These anomalies can lead to life-threatening conditions such as myocardial infarction, rupture, cardiac tamponade, and heart failure.

CASE SUMMARY

A 73-year-old male with chronic kidney failure was admitted for a preoperative cardiovascular assessment. Initially, he did not report any chest pain. However, while awaiting myocardial perfusion scintigraphy, he developed chest pain and coughing, leading him to present to the emergency department, where his troponin levels were found to be elevated. Coronary angiography and coronary computed tomography angiography showed a dual left coronary artery where one of the left anterior descending arteries completely transforms into a congenital aneurysm and fistula. In order to reshape the aneurysm neck and prevent the migration of coils into the left main coronary artery by creating a landing zone and to reduce the number of coils and the procedure time, two stents were first placed inside the aneurysm neck. Then, the fistula and aneurysm were successfully closed by coil implantation.

DISCUSSION

Some case studies and centre experiences recommend interventional closure using cover stents, vascular plugs, and coil embolization techniques for symptomatic fistulae and those resulting in complications. Despite these recommendations, determining the best treatment strategy remains challenging due to the lack of clear guidelines. The novel modified technic consisted of two nested stents and coil embolization to close the aneurysm and fistula and prevent secondary complications due to myocardial infarction.

摘要

背景

左前降支冠状动脉重复及冠状动脉-肺动脉瘘是文献中描述的罕见先天性异常。这些异常可导致危及生命的情况,如心肌梗死、破裂、心脏压塞和心力衰竭。

病例摘要

一名73岁慢性肾衰竭男性因术前心血管评估入院。最初,他未报告任何胸痛症状。然而,在等待心肌灌注闪烁扫描时,他出现了胸痛和咳嗽症状,随后前往急诊科就诊,检查发现其肌钙蛋白水平升高。冠状动脉造影和冠状动脉计算机断层扫描血管造影显示左冠状动脉双支,其中一支左前降支完全转变为先天性动脉瘤和瘘管。为了重塑动脉瘤颈部,通过创建着陆区防止线圈移入左主干冠状动脉,并减少线圈数量和手术时间,首先在动脉瘤颈部植入了两枚支架。然后,通过线圈植入成功闭合了瘘管和动脉瘤。

讨论

一些病例研究和中心经验推荐使用覆膜支架、血管封堵器和线圈栓塞技术对有症状的瘘管及导致并发症的瘘管进行介入封堵。尽管有这些推荐,但由于缺乏明确的指南,确定最佳治疗策略仍然具有挑战性。这种新型改良技术包括使用两枚嵌套支架和线圈栓塞来闭合动脉瘤和瘘管,并预防心肌梗死引起的继发性并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/12209800/4e4891fceba2/ytaf263f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/12209800/5757bd89068b/ytaf263il2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/12209800/c773bcf4c0fc/ytaf263f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/12209800/4ccbb689c6ba/ytaf263f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/12209800/2f182aa0cdee/ytaf263f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/12209800/4e4891fceba2/ytaf263f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/12209800/5757bd89068b/ytaf263il2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/12209800/c773bcf4c0fc/ytaf263f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/12209800/4ccbb689c6ba/ytaf263f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/12209800/2f182aa0cdee/ytaf263f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f71/12209800/4e4891fceba2/ytaf263f4.jpg

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本文引用的文献

1
Spontaneous thrombosis of a giant aneurysm complicated with the coronary-to-pulmonary artery fistula: a case report.巨大动脉瘤自发血栓形成合并冠状动脉-肺动脉瘘:一例报告
Eur Heart J Case Rep. 2024 Apr 26;8(5):ytae227. doi: 10.1093/ehjcr/ytae227. eCollection 2024 May.
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Acute myocardial infarction due to giant coronary artery aneurysm and arteriovenous fistula: a challenging case report and review of the literature.巨大冠状动脉瘤伴动静脉瘘致急性心肌梗死 1 例:挑战性病例报告及文献复习
BMC Cardiovasc Disord. 2024 Apr 1;24(1):187. doi: 10.1186/s12872-024-03851-w.
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Coronary Artery Fistulas: Indications, Techniques, Outcomes, and Complications of Transcatheter Fistula Closure.
冠状动脉瘘:经导管瘘口封堵的适应证、技术、结果和并发症。
JACC Cardiovasc Interv. 2021 Jul 12;14(13):1393-1406. doi: 10.1016/j.jcin.2021.02.044.
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Dual left anterior descending artery: diagnostic criteria and novel classification.双左前降支动脉:诊断标准与新分类
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Management of Coronary Artery Aneurysms.冠状动脉瘤的处理。
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