McClure Jennifer B
Center for Health Studies, Group Health Cooperative, Seattle, Washington 98101, USA.
Am J Prev Med. 2002 Apr;22(3):200-7. doi: 10.1016/s0749-3797(01)00425-1.
Nearly half of the leading causes of death in our society are attributable to behavioral risk factors. As such, it is critical that we continue to develop and refine effective interventions for health behavior change. Some researchers have suggested that using biomarkers to educate individuals about their health status and disease risk may be an effective strategy to promote behavior change. This tactic is also commonly employed by healthcare providers, but its empirical support is unclear. This article reviews the research literature to determine the effectiveness of using biomarker feedback to motivate and enable health behavior change. Potential limitations of this treatment strategy and issues requiring additional research are also discussed.
Articles were identified through PubMed (MEDLINE), PsychInfo, and the reference lists of pertinent manuscripts and book chapters.
Eight published, randomized trials were identified that met criteria for review. The results of this work were mixed, but suggest that biological information conveying harm exposure, disease risk, or impaired physical functioning may increase motivation to change. Subsequent behavior change is also affected by the availability and intensity of concomitant treatment.
Preliminary findings suggest that combining biomarkers with appropriate behavioral treatment may enhance health behavior change, but more research in this area is warranted.
在我们的社会中，近一半的主要死因可归因于行为风险因素。因此，我们继续开发和完善有效的健康行为改变干预措施至关重要。一些研究人员认为，使用生物标志物来让个体了解自己的健康状况和疾病风险可能是促进行为改变的有效策略。医疗保健提供者也普遍采用这种策略，但其实证支持尚不清楚。本文回顾了研究文献，以确定使用生物标志物反馈来激发和促成健康行为改变的有效性。还讨论了这种治疗策略的潜在局限性以及需要进一步研究的问题。
通过PubMed（医学文献数据库）、PsychInfo以及相关手稿和书籍章节的参考文献列表来识别文章。
确定了八项已发表的符合综述标准的随机试验。这项工作的结果参差不齐，但表明传达有害暴露、疾病风险或身体功能受损的生物学信息可能会增加改变的动机。随后的行为改变也受到伴随治疗的可用性和强度的影响。
初步研究结果表明，将生物标志物与适当的行为治疗相结合可能会增强健康行为改变，但该领域需要更多研究。
