Aasen A J, Hlubucek J R, Enzell C R
Acta Chem Scand B. 1975;29(6):677-81. doi: 10.3891/acta.chem.scand.29b-0677.
The structure of a new C15-lactone, (7S)-10-oxo-4xi-methyl-7-isopropyl-5E-undecen-4-olide, isolated from Greek tobacco, has been determined mainly be 1H NMR, 13C NMR and high resolution MS, and its absolute configuration established by degradation to (2S)-5-oxo-2-isopropylhexanal. The carbon skeleton of the new compound indicated that it is derived from a thunbergane precursor and constitutes the first C15 nor-thunberganoid in tobacco.
从希腊烟草中分离出的一种新的C15内酯，即(7S)-10-氧代-4ξ-甲基-7-异丙基-5E-十一碳烯-4-内酯，其结构主要通过1H NMR、13C NMR和高分辨率质谱测定，并通过降解为(2S)-5-氧代-2-异丙基己醛确定其绝对构型。新化合物的碳骨架表明它源自一个thunbergane前体，是烟草中首个C15去甲thunberganoid。
