Antibiotic phenol nor-triterpenes from Maytenus canariensis.
作者信息
González A G, Alvarenga N L, Ravelo A G, Jiménez I A, Bazzocchi I L, Canela N J, Moujir L M
机构信息
Instituto Universitario de Bio-Orgánica Antonio González, Universidad de La Laguna, Tenerife, Canary Islands, Spain.
出版信息
Phytochemistry. 1996 Sep;43(1):129-32. doi: 10.1016/0031-9422(96)00205-1.
PMID:8987507
Abstract
The new phenols 6-oxo-tingenol, 3-O-methyl-6-oxo-tingenol and 6-oxo-iguesterol were isolated from the root bark of Maytenus canariensis. Their structures were determined by 1H and 13C NMR spectroscopic studies, including HMQC, HMBC, DEPT and ROESY and chemical transformations. The synthesis of 6-oxo-tingenol was achieved from tingenone. These compounds exhibit antibiotic activity against Gram-positive bacteria.
摘要
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