Acta Eur Fertil. 1975 Mar;6(1):1-26.
A retrospective study was carried out in 224 sterile couples examined at the Obstetric and Gynecological Clinic of Genoa University for diagnosis and treatment. The study was performed between November 1, 1970 and May 31, 1973. Secondary sterility was not included. Altogether 84 pregnancies were obtained which amounts to a success rate of 37.5%. Of these 84 pregnancies, 15 started after hysterosalpingography and 17 occurred in couples who had not been given any treatment. Gonadotropin therapy yielded good results in cases treated for anovulation (30% pregnancies) and for slight oligoasthenospermia (32.65% pregnancies). Clomiphene treatment, too, gave good results, with 50% pregnancies. In sterility probably due to inflammatory conditions, the success rate obtained by medical treatment with 12%, while surgical management of tubal occlusions, performed in six cases, yielded only one pregnancy; a single pregnancy was equally obtained in three cases of uterine malformation submitted to Strassmann's operation. Also, only one pregnancy followed surgical treatment of the male partner (ligature of the left internal spermatic vein) in three cases of oligoasthenospermia. Among the couples where deficiencies could be ascertained in both partners, 33.33% of the women became pregnant. As for the evolution of the pregnancies obtained, only 9.52% aborted and 2.39% were ectopic.
对在热那亚大学妇产科诊所接受诊断和治疗的224对不育夫妇进行了一项回顾性研究。该研究于1970年11月1日至1973年5月31日期间进行。不包括继发性不育。总共获得了84次妊娠,成功率为37.5%。在这84次妊娠中,15次在子宫输卵管造影术后开始,17次发生在未接受任何治疗的夫妇中。促性腺激素疗法在治疗无排卵(妊娠率30%)和轻度少弱精子症(妊娠率32.65%)的病例中取得了良好效果。克罗米芬治疗也取得了良好效果,妊娠率为50%。在可能由炎症引起的不育症中,药物治疗的成功率为12%,而对6例输卵管阻塞进行的手术治疗仅产生了1次妊娠;对3例子宫畸形进行施特拉斯曼手术也仅获得了1次妊娠。此外,在3例少弱精子症病例中,对男性伴侣进行手术治疗(结扎左侧精索内静脉)后也仅产生了1次妊娠。在双方都有缺陷的夫妇中,33.33%的女性怀孕。至于所获得妊娠的进展情况,只有9.52%的妊娠流产,2.39%为异位妊娠。