Asheg A A, Fedorová V, Pistl J, Levkut M, Revajová V, Kolodzieyski L, Sevcíková Z, Pilipcinec E
Department of Pathological Anatomy, University of Veterinary Medicine, 041 81 Kosice, Slovakia.
Folia Microbiol (Praha). 2001;46(5):459-62. doi: 10.1007/BF02814439.
Chicks (1-d-old, three groups, each containing 50 chicks) were inoculated with 2 x 10(2) and 2 x 10(8) CFU of Salmonella enteritidis; the third group were kept as uninoculated control. Five birds from each group were euthanized at intervals from 6 h to 4 weeks post-inoculation (pi). In the low-dose group S. enteritidis was isolated from 60% cecal samples at 18 h pi, and from 20% of livers at 3 d pi. Individual variation in the frequency of S. enteritidis recovery was observed in this group. The clearance of salmonella from the organs was faster in the low-dose group, and salmonella was not isolated from the liver and cecum at 21 and at 27 d pi, respectively. However, in the high-dose group, S. enteritidis was isolated from all ceca and 80% of liver 6 h pi, and salmonella was detected in the cecum and liver throughout the experiment. Serous typhlitis and unabsorbed yolk sac were the most prevalent lesions in both groups. Granulomatous nodules in the cecum were found occasionally in some cases in both inoculated groups, which can play a role as reservoirs in carrier chicks.
将1日龄雏鸡分为三组，每组50只，分别接种2×10²和2×10⁸CFU肠炎沙门氏菌；第三组作为未接种的对照。接种后6小时至4周期间隔处死每组5只鸡。在低剂量组中，接种后18小时，60%的盲肠样本中分离出肠炎沙门氏菌，接种后3天，20%的肝脏中分离出该菌。该组中肠炎沙门氏菌检出频率存在个体差异。低剂量组中沙门氏菌从器官中的清除速度更快，接种后21天和27天，肝脏和盲肠中分别未分离出沙门氏菌。然而，在高剂量组中，接种后6小时，所有盲肠和80%的肝脏中均分离出肠炎沙门氏菌，并且在整个实验过程中，盲肠和肝脏中均检测到沙门氏菌。浆液性盲肠炎和未吸收的卵黄囊是两组中最常见的病变。在两个接种组的一些病例中，偶尔在盲肠中发现肉芽肿性结节，其可作为携带雏鸡的菌库。
