Desmidt M, Ducatelle R, Haesebrouck F
Department of Pathology, Bacteriology and Poultry Diseases, University of Gent, Merelbeke, Belgium.
Poult Sci. 1998 Jan;77(1):73-4. doi: 10.1093/ps/77.1.73.
One-day-old specific-pathogen-free White Leghorn chicks were inoculated orally with Salmonella enteritidis phage type 4 to study adhesion and invasion of the ceca by immunohistochemistry. Positive staining bacilli were associated with the epithelial surface and were present in the lumen of the cecal crypts. They were observed in the interstitial tissue and in the cytoplasm of macrophage-like cells in the lamina propria. A granulomatous nodule containing positive staining bacilli was present in the submucosa of the cecum of one bird at 14 d after inoculation.
为了通过免疫组织化学研究肠炎沙门氏菌4型对1日龄无特定病原体白来航雏鸡盲肠的黏附和侵袭情况，将其经口接种肠炎沙门氏菌4型。阳性染色杆菌与上皮表面相关，存在于盲肠隐窝腔内。在固有层的间质组织和巨噬细胞样细胞的细胞质中也观察到了它们。接种后14天，在一只鸡的盲肠黏膜下层出现了一个含有阳性染色杆菌的肉芽肿结节。
