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The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung.

作者信息

McCormack Francis X, Whitsett Jeffrey A

机构信息

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45267-0564, USA.

出版信息

J Clin Invest. 2002 Mar;109(6):707-12. doi: 10.1172/JCI15293.

DOI:10.1172/JCI15293
PMID:11901176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC150919/
Abstract
摘要

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本文引用的文献

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Properties, function and origin of the alveolar lining layer.肺泡衬里层的特性、功能及起源
Nature. 1955 Jun 25;175(4469):1125-6. doi: 10.1038/1751125b0.
2
Surfactant protein D enhances clearance of influenza A virus from the lung in vivo.表面活性蛋白D可增强甲型流感病毒在体内从肺中的清除。
J Immunol. 2001 Nov 15;167(10):5868-73. doi: 10.4049/jimmunol.167.10.5868.
3
The collagen-like region of surfactant protein A (SP-A) is required for correction of surfactant structural and functional defects in the SP-A null mouse.表面活性蛋白A(SP-A)的胶原样区域是纠正SP-A基因敲除小鼠表面活性剂结构和功能缺陷所必需的。
J Biol Chem. 2001 Oct 19;276(42):38542-8. doi: 10.1074/jbc.M102054200. Epub 2001 Aug 14.
4
Surfactant protein D regulates NF-kappa B and matrix metalloproteinase production in alveolar macrophages via oxidant-sensitive pathways.表面活性蛋白D通过氧化敏感途径调节肺泡巨噬细胞中核因子-κB和基质金属蛋白酶的产生。
J Immunol. 2001 Jun 15;166(12):7514-9. doi: 10.4049/jimmunol.166.12.7514.
5
Immunosuppressed surfactant protein A-deficient mice have increased susceptibility to Pneumocystis carinii infection.免疫抑制且缺乏表面活性蛋白A的小鼠对卡氏肺孢子虫感染的易感性增加。
J Infect Dis. 2001 Mar 15;183(6):943-52. doi: 10.1086/319252. Epub 2001 Feb 15.
6
Surfactant protein A differentially regulates IFN-gamma- and LPS-induced nitrite production by rat alveolar macrophages.表面活性蛋白A对大鼠肺泡巨噬细胞中干扰素-γ和脂多糖诱导的亚硝酸盐生成具有不同的调节作用。
Am J Respir Cell Mol Biol. 2000 Dec;23(6):772-9. doi: 10.1165/ajrcmb.23.6.4083.
7
Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lung.细菌感染期间表面活性蛋白A或D缺乏对肺部的不同影响。
J Immunol. 2000 Oct 1;165(7):3934-40. doi: 10.4049/jimmunol.165.7.3934.
8
Salivary agglutinin, which binds Streptococcus mutans and Helicobacter pylori, is the lung scavenger receptor cysteine-rich protein gp-340.唾液凝集素可结合变形链球菌和幽门螺杆菌,它是肺清道夫受体富含半胱氨酸蛋白gp-340。
J Biol Chem. 2000 Dec 22;275(51):39860-6. doi: 10.1074/jbc.M006928200.
9
Role of pulmonary surfactant protein D in innate defense against Candida albicans.肺表面活性蛋白D在抗白色念珠菌天然免疫防御中的作用
J Infect Dis. 2000 Sep;182(3):917-22. doi: 10.1086/315799. Epub 2000 Aug 17.
10
Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice.表面活性蛋白D基因失活小鼠的金属蛋白酶活性增加、氧化剂生成增加以及肺气肿
Proc Natl Acad Sci U S A. 2000 May 23;97(11):5972-7. doi: 10.1073/pnas.100448997.