Schmid Rudenz, Hermann Marianne, Yannar Ahmet, Baumgartner Ralf W
Neurologische Kliniken, Universitätsspital Zürich, Schweiz.
Ophthalmologica. 2002 Jan-Feb;216(1):16-21. doi: 10.1159/000048291.
The diagnosis of temporal arteritis (TA) is generally confirmed by biopsy. To investigate the diagnostic accuracy of color duplex sonography (CDS), both temporal arteries of 20 patients with suspected TA were prospectively insonated prior to biopsy. Detection of >or=1 hypoechogenic perivascular halo was used as CDS criterion, a temporal artery biopsy and the criteria of the American College of Rheumatology (ACR) as references. The frequency of halo disappearance after 3 months of steroid therapy was also studied. CDS showed TA in 6, biopsy in 12 and ACR criteria in 15 patients. CDS sensitivity was 50 and 40%, and specificity 100%, using the biopsy and the ACR criteria, respectively. After 3 months of steroid treatment, 1 patient still showed halos. In conclusion, detection of halos confirms, whereas the absence of halos does not exclude the diagnosis of TA suggesting that ultrasound may replace biopsy in single patients with typical clinical signs and symptoms and a halo.
颞动脉炎(TA)的诊断通常通过活检来确诊。为研究彩色双功能超声(CDS)的诊断准确性,在活检前对20例疑似TA患者的双侧颞动脉进行前瞻性超声检查。以检测到≥1个低回声血管周围晕环作为CDS标准,以颞动脉活检及美国风湿病学会(ACR)标准作为对照。还研究了类固醇治疗3个月后晕环消失的频率。CDS显示6例为TA,活检显示12例为TA,ACR标准显示15例为TA。分别以活检和ACR标准为对照时,CDS的敏感性分别为50%和40%,特异性为100%。类固醇治疗3个月后,1例患者仍有晕环。总之,检测到晕环可确诊TA,而未检测到晕环不能排除TA的诊断,这表明对于有典型临床体征和症状且出现晕环的单一患者,超声检查可能可替代活检。