Wissing U E, Ek A C, Wengström Y, Sköld G, Unosson M
Department of Medicine and Care, Division of Nursing Science, Faculty of Health Sciences, Linkoping University, Sweden.
J Wound Care. 2002 Jan;11(1):15-20. doi: 10.12968/jowc.2002.11.1.26127.
This study investigated whether an individually designed programme of nutritional support can improve healing in otherwise therapy-resistant venous leg ulcers.
Six primary health-care patients, aged between 79 and 93 years, with venous ulcers that had been open for one year or more (range: 1.5-8 years) were recruited into the study. The patients were asked to follow an individualised diet plan which included the use of liquid dietary supplements. Ulcer area, anthropometric and biochemical variables, and energy and nutrient intake were assessed before intervention and then regularly for nine months.
At nine months ulcer healing had occurred in two patients, of whom one had had ulcers on both legs. In a third patient the ulceration on one leg had healed and that on the other leg had almost healed. In a fourth patient, the ulcer area reduced by approximately 90%.
The use of nutritional support might have assisted the wound healing in these patients. Although the relationship between nutritional supplementation and wound healing is not well defined, an appropriate nutritional plan is recommended if undernourishment is suspected and leg ulcers are not healing.
本研究调查了个体化设计的营养支持方案是否能改善其他治疗方法难以治愈的下肢静脉溃疡的愈合情况。
招募了6名年龄在79至93岁之间、患有已开放一年或更长时间（范围：1.5至8年）的静脉溃疡的初级卫生保健患者参与该研究。要求患者遵循个性化饮食计划，其中包括使用液体膳食补充剂。在干预前评估溃疡面积、人体测量和生化变量以及能量和营养摄入情况，然后在九个月内定期进行评估。
九个月时，两名患者的溃疡已愈合，其中一名患者双腿都有溃疡。第三名患者一条腿上溃疡已愈合，另一条腿上的溃疡几乎愈合。第四名患者的溃疡面积减少了约90%。
营养支持的使用可能有助于这些患者的伤口愈合。尽管营养补充与伤口愈合之间的关系尚未明确界定，但如果怀疑营养不良且腿部溃疡未愈合，建议制定适当的营养计划。
