Sünder A, Flachowsky G
Institute of Animal Nutrition of the Federal Agricultural Research Centre, Braunschweig (FAL), Germany.
Arch Tierernahr. 2001;55(1):43-52. doi: 10.1080/17450390109386181.
The aim of the study was to contribute to the discussion of overdosing vitamin E in laying hens. A total of 45 laying hens, divided into 5 groups were fed diets supplemented with either 0; 100; 1000; 10,000 or 20,000 mg dl-alpha-tocopheryl acetate/kg diet over a period of 10 weeks. Concentrations of vitamins A and E were measured in plasma, various tissues and egg yolk. Furthermore egg yolk colour and some carotinoids were measured in egg yolks. None of the vitamin E doses significantly influenced performance of the hens. As expected, vitamin E concentration in plasma, all tissue samples and egg yolk was significantly increased with increasing tocopherol content in the diet. The egg yolk showed the highest vitamin E concentration, followed by liver and muscles. Feeding 1000 mg alpha-tocopheryl acetate per kg diet resulted in an increase of vitamin A concentration in the liver. Very high doses (10,000 and 20,000 mg/kg diet) significantly decreased retinol concentration in the liver and egg yolk, as well as carotinoid concentration in the egg yolk. The lower carotinoid concentration in egg yolk resulted in a decreased intensity of egg yolk colour. A prooxidative and/or competitive effect of very high doses of vitamin E with other fat soluble substances has been discussed.
本研究的目的是为蛋鸡过量摄入维生素E的讨论提供参考。总共45只蛋鸡被分为5组，在10周的时间里分别饲喂添加了0；100；1000；10000或20000毫克dl-α-生育酚醋酸酯/千克日粮的饲料。测定了血浆、各种组织和蛋黄中维生素A和E的浓度。此外，还测定了蛋黄的颜色和一些类胡萝卜素。没有一个维生素E剂量对母鸡的生产性能有显著影响。正如预期的那样，随着日粮中生育酚含量的增加，血浆、所有组织样本和蛋黄中的维生素E浓度显著升高。蛋黄中的维生素E浓度最高，其次是肝脏和肌肉。每千克日粮饲喂1000毫克α-生育酚醋酸酯会导致肝脏中维生素A浓度增加。非常高的剂量（10000和20000毫克/千克日粮）会显著降低肝脏和蛋黄中的视黄醇浓度以及蛋黄中的类胡萝卜素浓度。蛋黄中较低的类胡萝卜素浓度导致蛋黄颜色变浅。已经讨论了非常高剂量的维生素E与其他脂溶性物质的促氧化和/或竞争作用。
