Kostreva D R, Zuperku E J, Purtock R V, Coon R L, Kampine J P
Am J Physiol. 1975 Oct;229(4):911-5. doi: 10.1152/ajplegacy.1975.229.4.911.
Six mongrel dogs anesthetized with sodium pentobarbital and paralyzed with gallamine triethiodide were studied on total cardiopulmonary bypass. This study verified the existence of right heart mechanoreceptors whose afferent nerves traverse the upper thoracic white rami communicantes. these mechanoreceptors were studied by observing changes in average maximum, and total nerve spike frequency when right atrial and right ventricular systolic and diastolic pressures were altered by means of intracardiac balloons. Receptors that responded to volume and pressure changes were found in both the right atrium and right ventricle. Nerve activity in these afferents increased with increasing right atrial and right ventricular pressures. These mechanoreceptors were more responsive in the upper physiological ranges of right heart pressures. In most nerve fibers studied, maximum activity occurred during both right atrial and right ventricular diastole.
对6只戊巴比妥钠麻醉并用三碘季铵酚麻痹的杂种犬进行了体外循环研究。本研究证实了右心机械感受器的存在，其传入神经穿过胸段上部的白交通支。通过心内气囊改变右心房和右心室的收缩压和舒张压时，观察平均最大和总神经冲动频率的变化来研究这些机械感受器。在右心房和右心室均发现了对容量和压力变化有反应的感受器。随着右心房和右心室压力的增加，这些传入神经的神经活动增强。这些机械感受器在右心压力的较高生理范围内反应更灵敏。在大多数研究的神经纤维中，最大活动发生在右心房和右心室舒张期。
