van Heerbeek Niels, Ingels K J A O, Rijkers G T, Zielhuis G A
Department of Otorhinolaryngology, University Medical Centre St. Radboud, Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands.
Clin Otolaryngol Allied Sci. 2002 Feb;27(1):50-6. doi: 10.1046/j.0307-7772.2001.00524.x.
An impaired Eustachian tube is assumed to be an important factor in the pathogenesis of different middle ear diseases. Therefore, several investigators have studied different treatment strategies to improve Eustachian tube function. The aim of this review is to provide a comprehensive summary of the results of these studies on improvement of tubal function. The English language literature was searched systematically to identify all articles that described the effect of different interventions on Eustachian tube function. Although the results were not uniform throughout the different studies and despite several restrictions of the reviewed studies, the results of this review indicate that the function may be improved by medical intervention. However, it seems premature to recommend any of the interventions reviewed in this paper to improve function in humans. More studies, preferably randomized, placebo-controlled trials, should be conducted to assess the efficacy of different interventions.
咽鼓管功能受损被认为是不同中耳疾病发病机制中的一个重要因素。因此,一些研究人员研究了不同的治疗策略以改善咽鼓管功能。本综述的目的是全面总结这些关于改善咽鼓管功能的研究结果。系统检索了英文文献,以识别所有描述不同干预措施对咽鼓管功能影响的文章。尽管不同研究的结果并不一致,且所综述的研究存在一些局限性,但本综述结果表明,医学干预可能改善咽鼓管功能。然而,推荐本文中所综述的任何一种干预措施来改善人类的咽鼓管功能似乎还为时过早。应该开展更多研究,最好是随机、安慰剂对照试验,以评估不同干预措施的疗效。