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Ki67蛋白:完美的骗局?

Ki67 protein: the immaculate deception?

作者信息

Brown D C, Gatter K C

机构信息

Department of Histopathology, Whittington Hospital, London, UK.

出版信息

Histopathology. 2002 Jan;40(1):2-11. doi: 10.1046/j.1365-2559.2002.01343.x.

Abstract

This article updates our previous review of Ki67 published in Histopathology 10 years ago. In this period the numbers of papers published featuring this antibody has increased 10-fold from 338 to 3489 indicating the considerable enthusiasm with which this antibody has been studied. This review attempts to provide an update on the characterization of the Ki67 protein, its function and its use as a prognostic or diagnostic tool.

摘要

本文更新了我们10年前发表在《组织病理学》上关于Ki67的综述。在此期间,以该抗体为主题发表的论文数量从338篇增加到3489篇,增长了10倍,这表明对该抗体的研究热情高涨。本综述试图就Ki67蛋白的特性、功能及其作为预后或诊断工具的应用提供最新信息。

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