Hamel Christian T, Blum Johannes, Harder Felix, Kocher Thomas
Department of Surgery, University Hospital of Basel, General Surgical Service, Spitalstrasse 21, 4031, Basel, Switzerland.
Acta Trop. 2002 Apr;82(1):1-5. doi: 10.1016/s0001-706x(02)00025-6.
In many parts of the world malaria still is a major medical problem. Heavy international and transcontinental traveling carries malaria to non-endemic areas. Practicing physicians must be aware of the common, but also the rare and severe complications of malaria. During malaria changes in splenic structure can result in asymptomatic enlargement or complications such as hematoma formation, rupture, hypersplenism, ectopic spleen, torsion, or cyst formation. An abnormal immunological response may result in massive splenic enlargement. Spontaneous rupture of the spleen is an important and life threatening complication of Plasmodium vivax infection, but is rarely seen in Plasmodium falciparum malaria. The ability to properly diagnose and manage these complications is important. Spleen-conserving procedures should be the standard whenever possible especially in patients with a high likelihood of future exposure to malaria.
在世界许多地区,疟疾仍然是一个主要的医学问题。频繁的国际和跨大陆旅行将疟疾带到了非流行地区。执业医师必须了解疟疾常见的、罕见的以及严重的并发症。在疟疾期间,脾脏结构的变化可导致无症状性肿大或出现诸如血肿形成、破裂、脾功能亢进、异位脾、扭转或囊肿形成等并发症。异常的免疫反应可能导致脾脏大量肿大。脾脏自发性破裂是间日疟原虫感染的一种重要且危及生命的并发症,但在恶性疟原虫疟疾中很少见。正确诊断和处理这些并发症的能力很重要。只要有可能,保脾手术应成为标准治疗方法,尤其是对于未来有高疟疾暴露可能性的患者。