病理性疟疾性脾破裂（SRPMS）的临床范围及处理：来自苏丹的简短病例系列
The clinical range and management of spontaneous rupture of the pathological malarial spleen (SRPMS): A short case series from Sudan.
作者信息
Eltahir Eltahir Ahmed, Ibnouf Mohamed Ahmed M, Ibnouf Mohammed M A M, Ahmed Mohamed H, Imam Mohammed Haroon, Ahmed Atif
机构信息
Surgery University of Elfashir, Darfur, Sudan.
Faculty of Medicine and Health Sciences, Omdurman Islamic University, Sudan.
出版信息
Int J Surg Case Rep. 2025 Feb;127:110818. doi: 10.1016/j.ijscr.2025.110818. Epub 2025 Jan 6.
INTRODUCTION
Spontaneous rupture of the pathological malarial spleen (SRPMS) is a rare condition with a mortality rate among travelers of approximately 38 %, whereas it was around 10 % for local citizens. The mortality rate for overwhelming post-splenectomy sepsis was reported to be about 50 %.
METHODS
A retrospective study was conducted from febraury2022 to July 2022. Baseline clinical presentations, management, and outcomes were recorded for analysis.
RESULTS
We present a brief series of eight patients with (SRPMS). Of them, five had successful conservative treatment, while three underwent splenectomy. Only one of them received Pneumococcal vaccine.
CONCLUSION
SRPMS is a rare complication of malaria infection, it can be managed non-surgically, and splenectomy is necessary for unstable patients. Post-surgery vaccination remains crucial to prevent severe infections.
引言
病理性疟疾脾脏自发性破裂（SRPMS）是一种罕见病症，旅行者中的死亡率约为38%，而当地居民的死亡率约为10%。据报道，暴发性脾切除术后败血症的死亡率约为50%。
方法
对2022年2月至2022年7月进行回顾性研究。记录基线临床表现、治疗及结果以进行分析。
结果
我们简要介绍了8例SRPMS患者。其中，5例保守治疗成功，3例行脾切除术。他们中只有1人接种了肺炎球菌疫苗。
结论
SRPMS是疟疾感染的一种罕见并发症，可采用非手术治疗，不稳定患者有必要行脾切除术。术后接种疫苗对于预防严重感染仍然至关重要。
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