Fechner Robert E
Robert E. Fechner Laboratory of Surgical Pathology, Department of Pathology, University of Virginia Health System, Charlottesville, Virginia 22908, USA.
Mod Pathol. 2002 Mar;15(3):221-8. doi: 10.1038/modpathol.3880519.
Surgical pathology had its beginnings in the late 1800s. A biopsy that gained much attention was from the larynx of Crown Prince Frederick in 1887. The tissue was seen by Rudolph Virchow and the clinical management of the Prince eventuated in a highly publicized furor. During the first half of the twentieth century, numerous entities in the head and neck were described by dozens of pathologists worldwide. The information was scattered in clinical journals for radiotherapists, general surgeons, and otolaryngologists. The first book on ear, nose, and throat pathology did not appear until 1947 and by 1956 two atlases were available. The book was "Histopathology of the Ear, Nose and Throat" by Eggston and Wolff (1947), and the atlases were the first Armed Forces Institute of Pathology (AFIP) fascicle on salivary gland tumors by Foote and Frazell (1954) and "An Atlas of Otolaryngic Pathology" by Ash and Raum (1956). Clinicopathologic studies accelerated in the 1960s as laryngeal conservation therapy evolved and radiation therapy became more sophisticated. The years 1968 and 1974 mark major events for the emergence of Head and Neck Pathology into a clear-cut discipline. In 1968, Vincent J. Hyams was appointed Director of Otolaryngic Pathology at the AFIP, and 1974 was the publication date of "Tumors of the Head and Neck" by John G. Batsakis. The past 25 years have been filled with hundreds of articles on new entities and the application of fresh technology to old entities. Specialized therapeutic approaches have demanded greater diagnostic precision. This paper touches on a few representative aspects in the history of Head and Neck Pathology during the past 130 years.
外科病理学始于19世纪后期。1887年，对王储腓特烈喉的一次活检备受关注。鲁道夫·魏尔啸查看了该组织，王储的临床治疗最终引发了一场备受瞩目的轰动。在20世纪上半叶，世界各地的几十位病理学家描述了头颈部的众多病变实体。这些信息分散在放射治疗师、普通外科医生和耳鼻喉科医生的临床期刊中。直到1947年才出现第一本关于耳、鼻、喉病理学的书籍，到1956年有了两本图谱。这本书是埃格斯顿和沃尔夫所著的《耳、鼻、喉组织病理学》（1947年），图谱分别是富特和弗雷泽尔所著的第一本武装部队病理研究所（AFIP）关于涎腺肿瘤的分册（1954年）以及阿什和劳姆所著的《耳鼻喉科病理学图谱》（1956年）。随着保喉治疗的发展以及放射治疗变得更加成熟，20世纪60年代临床病理研究加速。1968年和1974年标志着头颈病理学成为一门明确学科过程中的重大事件。1968年，文森特·J·海姆斯被任命为AFIP耳鼻喉科病理学主任，1974年是约翰·G·巴塔基斯所著的《头颈部肿瘤》的出版年份。在过去的25年里，有成百上千篇关于新病变实体以及将新技术应用于旧实体的文章。专门的治疗方法要求更高的诊断精度。本文探讨了过去130年头颈病理学历史中的一些代表性方面。
