Folz Benedikt J, Silver Carl E, Rinaldo Alessandra, Fagan Johannes J, Pratt Loring W, Weir Neil, Seitz Daniela, Ferlito Alfio
Department of Otorhinolaryngology, Head and Neck Surgery, Karl Hansen Medical Center, Bad Lippspringe, Germany.
Oral Oncol. 2008 Jan;44(1):2-9. doi: 10.1016/j.oraloncology.2007.05.007. Epub 2007 Jul 30.
This review analyzes the development of head and neck oncology as outlined in medical history articles. A systematic literature survey was conducted with the search engines "Google Scholar" and "PubMed" and the retrieved publications were cross-referenced. In addition, books and, when possible, original sources were consulted. While most of the material was obtained from publications from the modern era reviewing historical data, some of the information was derived from original source material. The obtained articles on the history of cancer were then analyzed for details on head and neck oncology. The cradle of oncology was located in ancient Egypt and Greece. The search showed that the first tumors treated in the head and neck were either cutaneous malignancies or cancers on the mucosal surfaces of the oral cavity. The origin, diagnosis and treatment of more deeply situated tumors of the larynx and hypopharynx remained obscure for many centuries. The medieval age brought little progress to medicine in general, and in head and neck oncology in particular, due to religious concerns. Renaissance medicine was characterized by advances in medicine and oncology made by systematic dissection studies of normal and pathologic anatomy. The 19th and 20th century reflect the development of head and neck oncology in the era of science based medicine. Almost all of our current understanding of head and neck oncology, our diagnostic methods and treatment strategies have been developed in these two centuries. The analysis showed that many oncologic problems, which occupy our minds today, were also concerns of our medical ancestors.
本综述分析了医学史文章中概述的头颈肿瘤学的发展。使用搜索引擎“谷歌学术”和“PubMed”进行了系统的文献检索,并对检索到的出版物进行了交叉引用。此外,还查阅了书籍,并尽可能参考了原始资料。虽然大部分资料来自回顾历史数据的现代出版物,但有些信息来自原始资料。然后对获得的关于癌症历史的文章进行分析,以获取头颈肿瘤学的详细信息。肿瘤学的摇篮位于古埃及和希腊。研究表明,头颈部最早治疗的肿瘤要么是皮肤恶性肿瘤,要么是口腔黏膜表面的癌症。几个世纪以来,喉和下咽更深部位肿瘤的起源、诊断和治疗一直不明。由于宗教因素,中世纪总体上医学进展甚微,尤其是头颈肿瘤学。文艺复兴时期的医学特点是通过对正常和病理解剖学的系统解剖研究推动了医学和肿瘤学的发展。19世纪和20世纪反映了基于科学的医学时代头颈肿瘤学的发展。我们目前对头颈肿瘤学的几乎所有理解、诊断方法和治疗策略都是在这两个世纪发展起来的。分析表明,许多当今困扰我们的肿瘤学问题,也是我们医学先辈所关注的。