Dueholm Margit, Lundorf Erik, Hansen Estrid S, Ledertoug Susanne, Olesen Frede
Department of Gynecology and Obstetrics, Aarhus University and Aarhus University Hospital, Denmark.
Am J Obstet Gynecol. 2002 Mar;186(3):409-15. doi: 10.1067/mob.2002.121725.
The purpose of this study was to evaluate and compare the accuracy of magnetic resonance imaging and transvaginal ultrasonography in myoma diagnosis, mapping, and measurement.
This was a double-blind study of 106 consecutive premenopausal women who underwent hysterectomy for benign reasons. Myomas (total, 257) were exactly mapped by magnetic resonance imaging and transvaginal ultrasonography; in each patient, we counted correctly identified myomas with pathologic position as true value.
The presence of myomas was detected with the same high level of precision by both methods (magnetic resonance imaging: sensitivity, 0.99; specificity, 0.86; transvaginal ultrasonography: sensitivity, 0.99; specificity, 0.91). The mean number of correctly identified myomas was significantly higher by magnetic resonance imaging than by transvaginal ultrasonography (mean difference, 0.51 +/- 1.03; P <.001), a difference that narrowed to 0.08 +/- 0.76 (P =.60) in 26 patients with 1 to 4 myomas and uterine volumes <375 mL. Magnetic resonance imaging and transvaginal ultrasonography myoma diameter measurements had equal and high accuracies in patients with 1 to 4 myomas.
Transvaginal ultrasonography is as efficient as magnetic resonance imaging in detecting myoma presence, but its capacity for exact myoma mapping falls short of that of magnetic resonance imaging, especially in large (>375 mL) multiple-myoma (>4) uteri.
本研究旨在评估和比较磁共振成像(MRI)和经阴道超声检查(TVU)在子宫肌瘤诊断、定位及测量方面的准确性。
这是一项针对106例因良性原因接受子宫切除术的绝经前女性的双盲研究。通过MRI和TVU对子宫肌瘤(共257个)进行精确的定位;在每位患者中,我们将病理位置明确的正确识别出的肌瘤数量作为真值。
两种方法在检测子宫肌瘤的存在方面具有同样高的精度(MRI:灵敏度,0.99;特异度,0.86;TVU:灵敏度,0.99;特异度,0.91)。MRI正确识别出的肌瘤平均数量显著高于TVU(平均差值,0.51±1.03;P<.001),在26例肌瘤数量为1至4个且子宫体积<375 mL的患者中,这一差值缩小至0.08±0.76(P = 0.60)。在肌瘤数量为1至4个的患者中,MRI和TVU对肌瘤直径的测量具有同等且较高的准确性。
TVU在检测子宫肌瘤存在方面与MRI同样有效,但其精确肌瘤定位能力不及MRI,尤其是在子宫体积较大(>375 mL)且肌瘤数量较多(>4个)的子宫中。