Takigami Masayoshi, Baba Takeo, Saitou Koji
Kushiro Neurosurgical Hospital.
No Shinkei Geka. 2002 Mar;30(3):301-6.
We report a case of symptomatic cervical carotid artery stenosis associated with fibromuscular dysplasia (FMD) successfully treated by percutaneous transluminal angioplasty (PTA). A 49-year-old female presented with repeated ischemic attacks of right hemiparesis and aphasia. Digital subtraction angiography revealed a string of beads appearance of the left internal carotid artery typical of the medial type of FMD, at the level of the C2 vertebra. Similar findings were also evident in the right internal carotid artery at the level of the C1 vertebra, but without significant narrowing. MR angiogram of the left carotid artery revealed a marked flow gap, suggestive of severe stenosis. Forty days after onset PTA was indicated for symptomatic FMD of the left internal carotid artery because of the relative difficulty in approaching and repairing this highly located lesion surgically. The stenotic lesion was very easily dilated without any procedural complications. Although angiography just after PTA showed slight residual irregularity of the wall, this smoothed up with time. Follow-up MR angiography 7 years after PTA demonstrated long-term patency without clinical evidence of deterioration. Patients with the medial type of FMD in the carotid artery seem to be excellent candidates for PTA.
我们报告了一例经皮腔内血管成形术(PTA)成功治疗的与纤维肌发育不良(FMD)相关的有症状的颈总动脉狭窄病例。一名49岁女性反复出现右半身轻瘫和失语的缺血性发作。数字减影血管造影显示,在C2椎体水平,左侧颈内动脉呈现典型的中膜型FMD的串珠样外观。在C1椎体水平的右侧颈内动脉也有类似表现,但无明显狭窄。左侧颈动脉的磁共振血管造影显示有明显的血流间隙,提示严重狭窄。发病40天后,由于手术接近和修复这个高位病变相对困难,对左侧颈内动脉有症状的FMD进行了PTA治疗。狭窄病变很容易扩张,没有任何手术并发症。尽管PTA术后即刻血管造影显示管壁有轻微残留不规则,但随着时间推移这种情况变得平滑。PTA术后7年的随访磁共振血管造影显示长期通畅,没有临床恶化的证据。颈动脉中膜型FMD患者似乎是PTA的理想候选者。