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[米诺环素所致的狼疮样疾病]

[Lupus-like disease due to minocycline].

作者信息

Marai Ibrahim, Shoenfeld Yehuda

机构信息

Department of Internal Medicine, Research Unit of Autoimmune Diseases, Chaim Sheba Medical Center, Tel-Hashaomer, Israel.

出版信息

Harefuah. 2002 Feb;141(2):151-2, 223, 222.

Abstract

Minocycline in another drug that can induce drug-induced lupus. Minocycline is frequently used for acne as a prolonged treatment, so it is important to be aware of the risks in this treatment. The risk ratio for the development of lupus due to minocycline is not known, but it seems to be low. We described a 26 year old female who was treated with minocycline due to acne. The treatment was complicated by rash and serological signs of lupus (antinuclear antibodies and anti-DNA antibodies). The aim of this article is to raise the level of awareness of this complication due to minocycline.

摘要

米诺环素是另一种可诱发药物性狼疮的药物。米诺环素常用于痤疮的长期治疗,因此了解这种治疗中的风险很重要。米诺环素导致狼疮的风险比率尚不清楚,但似乎较低。我们描述了一名26岁因痤疮接受米诺环素治疗的女性。治疗过程中出现了皮疹和狼疮的血清学迹象(抗核抗体和抗DNA抗体)。本文旨在提高对米诺环素所致这种并发症的认识水平。

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