Bhattacharya J
Computation and Neural Systems, California Institute of Technology, MC 139-74, Pasadena, CA 91125, USA.
Acta Neurobiol Exp (Wars). 2001;61(4):309-18. doi: 10.55782/ane-2001-1406.
In this paper multivariate spontaneous EEG signals from three broad groups of human subjects--control, seizure, and mania--were studied with the aim of investigating the possible effect of these pathologies on the degree of phase synchronization between cortical areas. The degree of phase synchrony was measured by two recently developed measures which are more suitable than classical indices like correlation or coherence when dealing with nonlinear and non-stationary signals like the EEG. Signals were reduced to seven frequency bands (delta, theta, alpha-1, alpha-2, beta-1, beta-2 and gamma) which were statistically compared between the normal and the other two groups. It was found that the degree of long-range synchrony was significantly reduced for both pathological groups as compared with the control group. No clear differences were found in the degrees of short-range synchrony.
在本文中，对来自三类广泛的人类受试者——对照组、癫痫组和躁狂症组——的多变量自发脑电图信号进行了研究，目的是调查这些病理状况对皮质区域之间相位同步程度的可能影响。相位同步程度通过最近开发的两种测量方法进行测量，在处理像脑电图这样的非线性和非平稳信号时，这两种方法比相关性或相干性等经典指标更适用。信号被缩减为七个频带（δ波、θ波、α1波、α2波、β1波、β2波和γ波），并在正常组和其他两组之间进行统计学比较。结果发现，与对照组相比，两个病理组的长程同步程度均显著降低。在短程同步程度方面未发现明显差异。
