Ferenczy A, Franco E
Pathology and Obstetrics and Gynecology, McGill University and the Sir Mortimer B Davis-Jewish General Hospital, Montréal, Québec, Canada.
Lancet Oncol. 2001 Jan;2(1):27-32. doi: 10.1016/S1470-2045(00)00192-3.
Evidence-based studies have shown that new techniques for cervical cancer screening have a higher diagnostic yield than conventional cervical cytology (Pap test). Automated screening devices that use liquid-based, thin-layer cytology and human papillomavirus DNA testing are likely to become the standard for routine primary screening for cervical cancer and its precursors in the 21st century. The increased initial expense of the new techniques will most certainly be absorbed by instituting longer intervals for safe primary screening, in both low-risk and high-risk populations. To make modern screening programmes even more effective, we must promote extensive public awareness campaigns about cervical cancer, a preventable disease.
循证研究表明，宫颈癌筛查的新技术比传统宫颈细胞学检查（巴氏试验）具有更高的诊断率。使用液基薄层细胞学和人乳头瘤病毒DNA检测的自动筛查设备很可能成为21世纪宫颈癌及其癌前病变常规初筛的标准。新技术增加的初始费用肯定会通过在低风险和高风险人群中延长安全初筛间隔时间来抵消。为使现代筛查计划更有效，我们必须开展广泛的关于宫颈癌（一种可预防疾病）的公众宣传活动。
