印度的宫颈癌与HPV疫苗接种
Cervical cancer in India and HPV vaccination.
作者信息
Kaarthigeyan K
机构信息
Department of Pediatrics, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India.
出版信息
Indian J Med Paediatr Oncol. 2012 Jan;33(1):7-12. doi: 10.4103/0971-5851.96961.
Abstract
Cervical cancer, mainly caused by Human Papillomavirus infection, is the leading cancer in Indian women and the second most common cancer in women worldwide. Though there are several methods of prevention of cervical cancer, prevention by vaccination is emerging as the most effective option, with the availability of two vaccines. Several studies have been published examining the vaccine's efficacy, immunogenicity and safety. Questions and controversy remain regarding mandatory vaccination, need for booster doses and cost-effectiveness, particularly in the Indian context.
摘要
宫颈癌主要由人乳头瘤病毒感染引起，是印度女性中最主要的癌症，也是全球女性中第二常见的癌症。尽管有多种预防宫颈癌的方法，但随着两种疫苗的问世，通过接种疫苗进行预防正成为最有效的选择。已经发表了几项研究，探讨该疫苗的有效性、免疫原性和安全性。关于强制接种疫苗、是否需要加强剂量以及成本效益等问题仍存在疑问和争议，尤其是在印度的背景下。
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本文引用的文献
1
Human papilloma virus vaccines and current controversy.人乳头瘤病毒疫苗与当前争议
Indian Pediatr. 2011 Mar;48(3):248; author reply 248-9.
2
Human papilloma virus vaccines and current controversy.人乳头瘤病毒疫苗与当前争议
Indian Pediatr. 2010 Aug;47(8):724-5.
3
Consensus recommendations on immunization, 2008.《2008年免疫接种共识建议》
Indian Pediatr. 2008 Aug;45(8):635-48.
4
Human papillomavirus and vaccination.人乳头瘤病毒与疫苗接种。
Mayo Clin Proc. 2008 Jun;83(6):701-6; quiz 706-7. doi: 10.4065/83.6.701.
5
Human papillomavirus and cervical cancer.人乳头瘤病毒与宫颈癌
Lancet. 2007 Sep 8;370(9590):890-907. doi: 10.1016/S0140-6736(07)61416-0.
6
Quadrivalent Human Papillomavirus Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP).四价人乳头瘤病毒疫苗：免疫实践咨询委员会（ACIP）的建议
MMWR Recomm Rep. 2007 Mar 23;56(RR-2):1-24.
7
American Cancer Society Guideline for human papillomavirus (HPV) vaccine use to prevent cervical cancer and its precursors.美国癌症协会关于使用人乳头瘤病毒（HPV）疫苗预防宫颈癌及其癌前病变的指南。
CA Cancer J Clin. 2007 Jan-Feb;57(1):7-28. doi: 10.3322/canjclin.57.1.7.
8
High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up.一种预防性四价人乳头瘤病毒6/11/16/18型L1病毒样颗粒疫苗在长达5年的随访期内具有高持续效力。
Br J Cancer. 2006 Dec 4;95(11):1459-66. doi: 10.1038/sj.bjc.6603469. Epub 2006 Nov 21.
9
Chapter 1: HPV in the etiology of human cancer.第1章：人乳头瘤病毒在人类癌症病因学中的作用
Vaccine. 2006 Aug 31;24 Suppl 3:S3/1-10. doi: 10.1016/j.vaccine.2006.05.115. Epub 2006 Jun 23.
10
Genital human papillomavirus infection.生殖器人乳头瘤病毒感染
Clin Infect Dis. 2006 Sep 1;43(5):624-9. doi: 10.1086/505982. Epub 2006 Jul 26.
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