Shakudo M, Inoue Y, Mochizuki K, Manabe T, Mura K, Matsu R, Oda J, Yamada R
Department of Radiology, Osaka City General Hospital, Osaka, Japan.
Osaka City Med J. 2001 Dec;47(2):127-35.
The aims of this study were two: (1) to compare the efficacy of fast MRI (breath-hold fast spin-echo T2-weighted and fast gradient-echo T1-weighted sequence) and ultrafast MRI (half-Fourier acquisition single-shot turbo spin-echo sequence) in evaluation of fetal central nervous system (CNS) abnormalities at late gestational age, and (2) to compare the capability of fast MRI and ultrafast MRI to assess fetal CNS abnormalities with that of prenatal ultrasonography (US). Forty-nine women with fetuses at gestational ages of 26-39 weeks underwent fast MRI (29 patients) or ultrafast MRI (20 patients). In detection of motion artifact, visualization of the lateral and 4th ventricles, and differentiation between gray and white matter in cerebral hemispheres, ultrafast MRI was significantly superior to fast MRI (p< 0.0001, Mann-Whitney U test). In 25 of 43 cases, US and MR diagnoses were the same and consistent with postnatal diagnosis. In 10 of 43 cases, MRI demonstrated findings additional to or different from those of US, and MR findings were confirmed postnatally. MRI, particularly ultrafast MRI, is useful for demonstrating CNS abnormalities in situations in which US is suggestive but not definitive.
（1）比较快速MRI（屏气快速自旋回波T2加权和快速梯度回波T1加权序列）和超快MRI（半傅里叶采集单次激发快速自旋回波序列）在评估孕晚期胎儿中枢神经系统（CNS）异常方面的疗效；（2）比较快速MRI和超快MRI与产前超声（US）评估胎儿CNS异常的能力。49例孕周为26 - 39周的孕妇接受了快速MRI检查（29例患者）或超快MRI检查（20例患者）。在检测运动伪影、侧脑室和第四脑室的可视化以及大脑半球灰质和白质的区分方面，超快MRI明显优于快速MRI（p < 0.0001，曼-惠特尼U检验）。在43例病例中的25例中，超声和磁共振诊断相同且与产后诊断一致。在43例病例中的10例中，磁共振成像显示出超声检查结果之外或与之不同的发现，且磁共振成像结果在产后得到证实。磁共振成像，尤其是超快磁共振成像，在超声检查提示但不明确的情况下，对于显示中枢神经系统异常很有用。
