Reichel Taylor F, Ramus Ronald M, Caire Jacqueline T, Hynan Linda S, Magee Kevin P, Twickler Diane M
Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-8896,USA.
AJR Am J Roentgenol. 2003 Apr;180(4):1155-8. doi: 10.2214/ajr.180.4.1801155.
We sought to compare the biometry of the fetal head on MR imaging with sonographic measurements in fetuses with and without suspected central nervous system abnormalities.
Blinded retrospective measurements of biparietal diameter, head circumference, and cerebellar width obtained on MR imaging were assigned a gestational age on the basis of median sonographic measurements and compared with sonographic and clinical assignment of gestational age in fetuses with no central nervous system abnormalities. In fetuses with central nervous system abnormalities, the same MR measurements were compared with sonographic measurements obtained within 1 week. Single-shot fast spin-echo sequences were obtained. Pearson's product moment correlation coefficients and paired sample t tests were performed.
In 22 fetuses with no suspected central nervous system abnormalities, significant correlation was seen in the assignment of gestational age by MR measurements and sonographic gestational age. In 25 fetuses with central nervous system abnormalities, significant correlation was also seen between biparietal diameter and head circumference measurements. The mean biparietal diameter on MR imaging was greater than on sonography in those fetuses with central nervous system abnormalities (p = 0.038).
MR imaging measurements of biparietal diameter, head circumference, and cerebellar width are strongly correlated to gestational age in fetuses without central nervous system abnormalities. Significant correlation is found between MR imaging and sonographic measurements of biparietal diameter and head circumference in fetuses with central nervous system abnormalities. Larger biparietal diameter measurements were seen with MR imaging than with sonography in the abnormal group. Fetal central nervous system biometry can be performed as part of the MR imaging evaluation of the fetal central nervous system.
我们试图比较磁共振成像（MR成像）上胎儿头部的生物测量值与超声测量值，这些胎儿有无可疑的中枢神经系统异常。
对MR成像上获得的双顶径、头围和小脑宽度进行盲法回顾性测量，根据超声测量中位数确定胎龄，并与无中枢神经系统异常胎儿的超声及临床确定的胎龄进行比较。对于有中枢神经系统异常的胎儿，将相同的MR测量值与1周内获得的超声测量值进行比较。采用单次激发快速自旋回波序列。进行Pearson积矩相关系数分析和配对样本t检验。
在22例无可疑中枢神经系统异常的胎儿中，MR测量确定的胎龄与超声确定的胎龄之间存在显著相关性。在25例有中枢神经系统异常的胎儿中，双顶径和头围测量值之间也存在显著相关性。在有中枢神经系统异常的胎儿中，MR成像上的平均双顶径大于超声测量值（p = 0.038）。
在无中枢神经系统异常的胎儿中，MR成像测量的双顶径、头围和小脑宽度与胎龄密切相关。在有中枢神经系统异常的胎儿中，MR成像与超声测量的双顶径和头围之间存在显著相关性。在异常组中，MR成像测得的双顶径大于超声测量值。胎儿中枢神经系统生物测量可作为胎儿中枢神经系统MR成像评估的一部分。
