Baker T P, Lenert J T, Parker J, Kemp B, Kushwaha A, Evans G, Hunt K K
Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
Breast J. 2001 Sep-Oct;7(5):354-7. doi: 10.1046/j.1524-4741.2001.20075.x.
This is a case of a large lactating adenoma which developed in a 26 year old primagravida during the third trimester of her pregnancy. The presentation was that of a grossly enlarged and engorged breast with breast erythema, warmth and tenderness. Radiologic and pathologic examinations were difficult because of the lactational changes in the breast and areas of infarcted tissue within the large tumor. Skin biopsies and core biopsies of the mass were performed to exclude malignancy. Surgical resection of the mass was necessary for definitive diagnosis. The pathology proved to be a lactating adenoma, which is the most prevalent breast mass in young pregnant females. The large size of this tumor, and the presentation of breast erythema and edema raised the possibility of inflammatory breast cancer. Following surgical resection and definitive diagnosis of this tumor, the patient required plastic surgical reconstruction of the breast because of redundant breast tissue. Although most lactating adenomas spontaneously involute, the diagnosis is not always straight-forward and surgical resection may be required for definitive diagnosis and exclusion of other pathologic processes.
这是一例发生在一名26岁初产妇妊娠晚期的巨大泌乳性腺瘤病例。临床表现为乳房明显肿大、充血，伴有乳房红斑、发热和压痛。由于乳房的泌乳变化以及大肿瘤内梗死组织区域，放射学和病理学检查困难。进行了皮肤活检和肿块的粗针活检以排除恶性肿瘤。为明确诊断，必须对肿块进行手术切除。病理结果证实为泌乳性腺瘤，这是年轻怀孕女性中最常见的乳腺肿块。该肿瘤体积巨大，且出现乳房红斑和水肿，增加了炎性乳腺癌的可能性。在对该肿瘤进行手术切除并明确诊断后，由于乳房组织冗余，患者需要进行乳房整形重建。尽管大多数泌乳性腺瘤会自发消退，但诊断并不总是简单直接的，可能需要手术切除以明确诊断并排除其他病理过程。
