对社区中65岁及以上老年人流感疫苗有效性的荟萃分析。
A meta-analysis of effectiveness of influenza vaccine in persons aged 65 years and over living in the community.
作者信息
Vu Trang, Farish Stephen, Jenkins Mark, Kelly Heath
机构信息
Victorian Public Health Training Program, Charles Connibere Building, The Royal Melbourne Hospital, Flemington Road, Parkville, Vic. 3050, Australia.
出版信息
Vaccine. 2002 Mar 15;20(13-14):1831-6. doi: 10.1016/s0264-410x(02)00041-5.
AIM
To estimate the effectiveness of inactivated influenza vaccine in persons aged 65 years and over living in the community.
SCOPE
A meta-analysis of studies selected using predetermined criteria without language restriction.
CONCLUSION
Influenza vaccine was effective in reducing influenza-like illness by 35% (95% confidence interval (CI) 19-47%), hospitalization for pneumonia and influenza by 33% (CI 27-38%), mortality following hospitalization for pneumonia and influenza by 47% (CI 25-62%); and mortality from all causes by 50% (CI 45-56%).
目的
评估社区中65岁及以上人群接种灭活流感疫苗的效果。
范围
对根据预定标准选择的研究进行荟萃分析，无语言限制。
结论
流感疫苗能有效降低35%的流感样疾病（95%置信区间（CI）为19%-47%）、33%的肺炎和流感住院率（CI为27%-38%）、47%的肺炎和流感住院后的死亡率（CI为25%-62%）以及50%的全因死亡率（CI为45%-56%）。
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