内皮素、肾病与血压。 - Suppr

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超能文献

Endothelin, nephropathy, and blood pressure.

作者信息

Luft Friedrich C

机构信息

Franz-Volhard-Klinik, Humboldt University of Berlin, Wiltbergstrasse 50, 13125 Berlin-Buch, Germany.

出版信息

J Mol Med (Berl). 2002 Feb;80(2):69-70. doi: 10.1007/s00109-001-0313-3. Epub 2002 Jan 31.

DOI:10.1007/s00109-001-0313-3

PMID:11907642

Abstract

摘要

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Endothelin, nephropathy, and blood pressure.内皮素、肾病与血压。

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Pathophysiology in endothelin-1 transgenic mice.内皮素-1转基因小鼠的病理生理学

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Targets for endothelin in the diseased kidney: clues for therapeutic intervention.疾病肾脏中内皮素的作用靶点：治疗干预线索

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Endothelin and heart transplantation.内皮素与心脏移植

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Inducible human endothelin-1 overexpression in endothelium raises blood pressure via endothelin type A receptors.内皮细胞中可诱导的人内皮素-1过表达通过A型内皮素受体升高血压。

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Endothelin receptors, renal effects and blood pressure.内皮素受体、肾脏效应与血压

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[Endothelins: possibly a new pharmacological approach in cardiovascular diseases, kidney diseases and oncological disorders].[内皮素：心血管疾病、肾脏疾病及肿瘤疾病治疗中可能的新药理学方法]

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Endothelin-1 overexpression restores diastolic function in eNOS knockout mice.内皮素-1 过表达可恢复 eNOS 敲除小鼠的舒张功能。

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本文引用的文献

Renal damage and salt-dependent hypertension in aged transgenic mice overexpressing endothelin-1.过表达内皮素-1的老年转基因小鼠的肾损伤和盐依赖性高血压

J Mol Med (Berl). 2002 Feb;80(2):105-16. doi: 10.1007/s00109-001-0284-4. Epub 2001 Nov 8.

Renal endothelin-1 and endothelin receptor type B expression in glomerular diseases with proteinuria.蛋白尿性肾小球疾病中肾内皮素-1及B型内皮素受体的表达

J Am Soc Nephrol. 2001 Nov;12(11):2321-2329. doi: 10.1681/ASN.V12112321.

Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study.双重内皮素受体拮抗剂波生坦治疗肺动脉高压患者的疗效：一项随机安慰剂对照研究。

Lancet. 2001 Oct 6;358(9288):1119-23. doi: 10.1016/S0140-6736(01)06250-X.

The effect of endothelin-1 on nuclear factor kappa B in macrophages.内皮素-1对巨噬细胞核因子κB的影响。

Biochem Biophys Res Commun. 2001 Sep 7;286(5):968-72. doi: 10.1006/bbrc.2001.5485.

The dual endothelin receptor antagonist tezosentan acutely improves hemodynamic parameters in patients with advanced heart failure.双重内皮素受体拮抗剂替唑生坦可迅速改善晚期心力衰竭患者的血流动力学参数。

Am Heart J. 2001 Aug;142(2):340-9. doi: 10.1067/mhj.2001.116760.

Endothelin system: the double-edged sword in health and disease.内皮素系统：健康与疾病中的双刃剑。

Annu Rev Pharmacol Toxicol. 2001;41:851-76. doi: 10.1146/annurev.pharmtox.41.1.851.

Effect of bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage.波生坦对血管紧张素II诱导的终末器官损伤中核因子κB、炎症及组织因子的影响。

Hypertension. 2000 Aug;36(2):282-90. doi: 10.1161/01.hyp.36.2.282.

Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension.内皮素-1转基因小鼠会出现肾小球硬化、间质纤维化和肾囊肿，但不会出现高血压。

J Clin Invest. 1997 Mar 15;99(6):1380-9. doi: 10.1172/JCI119297.

Endothelin-dependent actions in cultured AT-1 cardiac myocytes. The role of the epsilon isoform of protein kinase C.内皮素在培养的AT-1心肌细胞中的依赖性作用。蛋白激酶C的ε亚型的作用。

Circ Res. 1996 Apr;78(4):724-36. doi: 10.1161/01.res.78.4.724.

Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways.大鼠肾脏中系膜细胞、肾小球及肾血管对内皮素的反应。信号转导途径的阐明。

J Clin Invest. 1989 Jan;83(1):336-42. doi: 10.1172/JCI113880.

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