Tarazov P G, Pavlovskij A V, Granov D A
St. Petersburg Research Institute of Roentgenology and Radiation Therapy, Russia.
Cardiovasc Intervent Radiol. 2001 Nov-Dec;24(6):424-6. doi: 10.1007/s00270-001-0040-8. Epub 2001 Nov 8.
Oily chemoembolization is a known method of treatment for hepatic malignancies but was never used for pancreatic cancer. We report the case of a 48-year-old patient with unresectable adenocarcinoma of the pancreatic head treated by repeated chemoembolizations of the feeding (gastroduodenal) artery with gemcitabine-in-lipiodol. After 10 procedures there was a marked decrease in tumor. Radiologic examinations showed no signs of viable tumor. The patient is alive and symptom-free 22 months after the start of treatment. Oily chemoembolization should be investigated as a technically simple, safe, and potentially effective palliative management of unresectable pancreatic head carcinoma.
油性化疗栓塞术是治疗肝脏恶性肿瘤的一种已知方法，但从未用于胰腺癌。我们报告了一例48岁不可切除胰头腺癌患者，采用吉西他滨-碘油对供血（胃十二指肠）动脉进行反复化疗栓塞治疗。经过10次治疗后，肿瘤明显缩小。影像学检查未显示有存活肿瘤的迹象。患者在治疗开始22个月后仍存活且无症状。油性化疗栓塞术作为一种技术上简单、安全且可能有效的不可切除胰头癌姑息治疗方法，值得进一步研究。
