[硫柳汞与铝封闭腔之间不存在相互作用]
[Absence of interaction between thiomersal and aluminum occlusion chambers].
作者信息
Assier-Bonnet H, Slimani S, Revuz J
机构信息
Service de Dermatologie, Hôpital Henri Mondor, Université Paris XII, Créteil.
出版信息
Ann Dermatol Venereol. 2001 Oct;128(10 Pt 1):1025-6.
BACKGROUND
Positive patch tests to thiomersal are frequent, but of little relevance. Interaction between aluminium occlusive chambers and the mercury of thiomersal may elicit skin irritation and cause false positive results.
METHODS
Between January 1998 and May 1999, the patients were simultaneously patch tested with aluminium and plastic chambers. Positive skin tests were compared.
RESULTS
Seventeen of 213 subjects showed positive tests: 15 with the 2 materials, 1 only for the aluminium chamber, 1 for the plastic chamber.
DISCUSSION
The results did not differ for the two materials. We concluded that positive reactions observed were not caused by interaction between aluminium and thiomersal.
背景
硫柳汞斑贴试验阳性很常见，但意义不大。铝制封闭小室与硫柳汞中的汞之间的相互作用可能会引起皮肤刺激并导致假阳性结果。
方法
1998年1月至1999年5月期间，对患者同时使用铝制和塑料制小室进行斑贴试验。比较皮肤试验阳性结果。
结果
213名受试者中有17人试验呈阳性：15人对两种材料均呈阳性，1人仅对铝制小室呈阳性，1人对塑料制小室呈阳性。
讨论
两种材料的结果无差异。我们得出结论，观察到的阳性反应不是由铝与硫柳汞之间的相互作用引起的。
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