Kopf A W, Mintzis M, Bart R S
Arch Dermatol. 1975 Oct;111(10):1291-2.
The diagnostic accuracy and index of suspicion concerning malignant melanoma were calculated based on review of 5,538 histologically examined lesions (of which 99 were melanomas) that were recorded in the Oncology Section of the Skin and Cancer Unit from 1955 to 1967. The diagnostic accuracy of the physicians in the Section was determined to be 64.4%. Thus, in almost one of every three melanomas an error in clinical diagnosis was made. This "batting average" is, however, better than those of previously published reports. The index of suspicion in relation to malignant melanoma in our series was 96%. Thus, the physicians in the Oncology Section demonstrated an appropriate awareness of this tumor. However, coupled with a diagnostic accuracy of 64%, a problem nevertheless exists in the diagnosis of this serious cutaneous cancer. Our study emphasizes the importance of having histologic verification prior to definitive radical surgery on patients with malignant melanoma.
基于对1955年至1967年皮肤与癌症科室肿瘤科记录的5538例经组织学检查的病变（其中99例为黑色素瘤）的回顾，计算了关于恶性黑色素瘤的诊断准确性和怀疑指数。该科室医生的诊断准确性被确定为64.4%。因此，几乎每三例黑色素瘤中就有一例临床诊断出现错误。然而，这个“成功率”比之前发表的报告要好。我们系列研究中与恶性黑色素瘤相关的怀疑指数为96%。因此，肿瘤科的医生对这种肿瘤表现出了适当的认识。然而，结合64%的诊断准确性，在这种严重皮肤癌的诊断中仍然存在问题。我们的研究强调了在对恶性黑色素瘤患者进行确定性根治手术之前进行组织学验证的重要性。
