来自非洲刺桐根皮的异戊烯基化异黄酮类化合物。

Prenylated isoflavonoids from the root bark of Erythrina vogelii.

作者信息

Queiroz Emerson F, Atindehou Kagoyire K, Terreaux Christian, Antus Sandor, Hostettmann Kurt

机构信息

Institut de Pharmacognosie et Phytochimie, Université de Lausanne, BEP, CH-1015 Lausanne, Switzerland.

出版信息

J Nat Prod. 2002 Mar;65(3):403-6. doi: 10.1021/np0103867.

DOI:10.1021/np0103867

PMID:11908991

Abstract

Four new prenylated isoflavonoids, vogelins D-G (1-4), were isolated from the CH2Cl2 extract of Erythrina vogelii root bark in addition to the known compounds isolupalbigenin (5), ficuisoflavone (6), ulexone (7), isochandalon (8), and isoderrone (9). The structures 1-4 were elucidated by spectroscopic and chemical methods. The absolute configuration of compound 1 was determined on the basis of its CD spectrum. Possible biogenetic relationships among the E. vogelii isoflavonoids are briefly discussed.

摘要

除了已知化合物异卢佩尔双黄酮（5）、无花果异黄酮（6）、刺酮（7）、异查耳酮（8）和异德龙（9）外，还从鸡冠刺桐根皮的二氯甲烷提取物中分离出4种新的异戊烯基化异黄酮，即沃格林D-G（1-4）。通过光谱和化学方法阐明了化合物1-4的结构。根据化合物I的圆二色谱确定了其绝对构型。简要讨论了鸡冠刺桐异黄酮之间可能的生源关系。