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在具有波动峰值的适应度景观上的准种进化。

Quasispecies evolution on a fitness landscape with a fluctuating peak.

作者信息

Nilsson Martin, Snoad Nigel

机构信息

Institute of Theoretical Physics, Chalmers University of Technology and Göteborg University, S-412 96 Göteborg, Sweden.

出版信息

Phys Rev E Stat Nonlin Soft Matter Phys. 2002 Mar;65(3 Pt 1):031901. doi: 10.1103/PhysRevE.65.031901. Epub 2002 Feb 7.

DOI:10.1103/PhysRevE.65.031901
PMID:11909103
Abstract

A quasispecies evolving on a fitness landscape with a single peak of fluctuating height is studied. In the approximation that back mutations can be ignored, the rate equations can be solved analytically. It is shown that the error threshold on this class of dynamic landscapes is defined by the time average of the selection pressure. In the case of a periodically fluctuating fitness peak, we also study the phase shift and response amplitude of the previously documented low-pass filter effect. The special case of a small harmonic fluctuation is treated analytically.

摘要

研究了在具有高度波动的单峰适应度景观上进化的准种。在可以忽略反向突变的近似情况下,速率方程可以解析求解。结果表明,这类动态景观上的误差阈值由选择压力的时间平均值定义。在适应度峰值周期性波动的情况下,我们还研究了先前记录的低通滤波效应的相移和响应幅度。对小谐波波动的特殊情况进行了解析处理。

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