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The dynamical way to mutation-selection balance of an infinite population evolving on a truncated fitness landscape.

作者信息

Maia Leonardo P

机构信息

Instituto de Ciências Matemáticas e de Computação, Universidade de São Paulo, 13560-970 São Carlos, SP, Brazil.

出版信息

J Math Biol. 2005 Jul;51(1):114-22. doi: 10.1007/s00285-005-0327-5. Epub 2005 May 2.

DOI:10.1007/s00285-005-0327-5
PMID:15868191
Abstract

This paper presents the exact analytical solution, valid for all generations and initial conditions, for the frequency distribution of haploids with infinite-sites genome carrying a given number of mutations in a population evolving deterministically on a truncated fitness landscape. This landscape is a generalization of the single sharp peak one, widely used in quasispecies theory, although here there are no reverse mutations.

摘要

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