Lipschutz Joshua H, Mostov Keith E
Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Curr Biol. 2002 Mar 19;12(6):R212-4. doi: 10.1016/s0960-9822(02)00753-4.
The exocyst is a conserved eight-subunit complex involved in the docking of exocytic vesicles. The exocyst has now been identified as an effector for five small GTPases, including Sec4, Rho1, Rho3, Cdc42 and, most recently, RalA.
外泌体分泌复合体是一种保守的八亚基复合体,参与胞吐小泡的对接。目前已确定外泌体分泌复合体是包括Sec4、Rho1、Rho3、Cdc42以及最近发现的RalA在内的五种小GTP酶的效应器。